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  1. 2 days ago · Generalized bullous fixed drug eruption (GBFDE) ... (>50% of total body surface area) pruritic morbilliform rash within 8 weeks (most commonly 2–6 weeks) of culprit drug exposure 27,68 ...

  2. 3 days ago · Drug hypersensitivity syndrome (also known as drug reaction with eosinophilia and systemic symptoms or DRESS) is an exanthematous eruption accompanied by fever, lymphadenopathy, and multiorgan involvement (kidneys, liver, lung, bone marrow, heart, and brain). Signs and symptoms begin 1 to 4 weeks after starting the offending drug, and the ...

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  4. 4 days ago · Some vascular reaction pattern diseases may develop vesicles and bullae, such as erythema multiforme, Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), and fixed drug eruption. Also, bullous pemphigoid may begin with urticarial plaques only—the prebullous phase—and then progress to bulla formation (see Figure 7.22). The ...

  5. 4 days ago · Morbilliform exanthematous reactions, fixed drug eruption, lichenoid eruptions, Stevens–Johnson syndrome, toxic epidermal necrolysis *After the Gell and Coombs classification of immune reactions. **For contact sensitivity see Section 2 .

  6. 3 days ago · The clinical picture is specific, the child presents in the emergency unit with fever, asthenia, and a morbilliform rash that can rapidly progress to erythroderma. Facial edema and oral cavity lesions are characteristic and raise an alarm signal: Hemorrhagic-necrotic cheilitis, pharyngitis, and stomatitis [Figures 5 and 6]. The most frequently ...

  7. 2 days ago · Bullous fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Bullous drug eruptions are infrequent, but because they pose a challenge both to affected patients and to treating physicians, they are considered to be the most severe cutaneous adverse reactions (SCAR).

  8. 5 days ago · These attributes of lesions and eruptions can be harnessed as diagnostic tools. As has been previously mentioned, shape is an inherent property of one individual lesion whereas configuration refers to the scheme or arrangement formed by confluent grouped lesions.

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