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4 days ago · Neonatal sepsis, a complex and heterogeneous condition produced as response to invasive blood infection mostly caused by bacteria, classified as early or late-onset, is one of the leading causes of mortality and morbidity during the neonatal period. Early onset sepsis (EOS) is defined as the presence of bacteremia or meningitis in the first ...
3 days ago · The period (2018–2021) prevalence of neonatal sepsis from the sample of 360 was 59%, with early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS) accounting for about 29% and 30%, respectively. These estimates translate to an average yearly prevalence of neonatal sepsis of 15%. Nonetheless, the disaggregated results as ...
1 day ago · Gram-negative bacteria (GNB) are a major cause of neonatal sepsis in low- and middle-income countries (LMICs). Although the World Health Organization (WHO) reports that over 80% of these sepsis ...
1 day ago · Maternal sepsis is a life-threatening medical emergency defined as organ dysfunction resulting from infection during pregnancy, childbirth, abortion, miscarriage, or the postpartum period. Neonatal sepsis describes sepsis in an infant’s first 28 days of life. The U.S. has the third highest rate of maternal mortality of all high-income ...
1 day ago · The study underscores the significance of histological fetal inflammatory response (FIR) in preterm infants born with histological chorioamnionitis (HCA), indicating its association with adverse neonatal outcomes such as early-onset sepsis (EOS), bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), and retinopathy of prematurity (ROP).
1 day ago · For late-onset sepsis (> 72 h), commonly linked to organisms acquired from the hospital environment, coagulase-negative staphylococci are the most common pathogens, although a broader spectrum of bacteria, including Staphylococcus aureus, GBS, Enterococcus, E. coli, and other Gram-negative bacteria, is also encountered.
5 days ago · Statistical analysis was per intention to treat. InterventionsRandom allocation to 1 of 3 groups (1:1:1) based on age: neonates younger than 6 hours were randomized to normothermia or 72-hour hypothermia (33.5 °C), and those 6 hours or older and already receiving whole-body hypothermia were randomized to rewarming after 48 or 72 hours of ...
