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- Sepsis results from the interaction of the infectious agent, usually bacteria, with the host’s immune, cardiovascular, neuronal, metabolic, and coagulation systems. Some degree of inflammatory response to infection is normal, but when this response is dysregulated, an excess of pro- and anti-inflammatory mediators leads to organ dysfunction.
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Apr 18, 2024 · Sepsis, systemic inflammatory condition that occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. Sepsis is a common cause of illness and mortality in hospitals. Learn more about the causes, symptoms, and treatment of sepsis.
- Kara Rogers
4 days ago · Microbial factors. Bacterial virulence factors, such as glycocalyx and various adhesins, allow colonization, immune evasion, and establishment of disease in the host. Sepsis caused by gram-negative bacteria is thought to be largely due to a response by the host to the lipid A component of lipopolysaccharide, also called endotoxin.
- May be rapid (less than three hours) or prolonged (several days)
- Immune response triggered by an infection
5 days ago · Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Evidence of organ dysfunction includes clinical and laboratory abnormalities of the respiratory system, coagulation, liver, cardiovascular system, nervous system, and kidneys (Table 79–1). + +
Apr 2, 2024 · Sepsis is a serious condition that most often occurs when an infection or toxic substance overwhelms your body's immune system, or when your immune system overreacts to an infection, toxic substance, or unidentified trigger.
Apr 1, 2024 · Sepsis is the immune system's overwhelming response to infection. It can lead to a dramatic drop in blood pressure that damages vital organs and causes death. Sepsis risk factors include older age,...
- Toni Golen, MD
- hhp_info@health.harvard.edu
Apr 9, 2024 · What is sepsis? Sepsis is when your body has an extreme response to an infection. It is a life- threatening condition and you need immediate medical attention. It can cause death or permanent damage to your body without treatment. Sepsis always starts with an infection.
Apr 12, 2024 · Septic shock, severe and potentially life-threatening condition characterized particularly by dangerously low blood pressure, confusion and disorientation, and organ dysfunction. Septic shock is the third and final stage of sepsis—a systemic inflammatory condition that occurs as a complication of.
