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  2. 5 days ago · Neonatal sepsis, a complex and heterogeneous condition produced as response to invasive blood infection mostly caused by bacteria, classified as early or late-onset, is one of the leading causes of mortality and morbidity during the neonatal period. Early onset sepsis (EOS) is defined as the presence of bacteremia or meningitis in the first ...

  3. 4 days ago · The period (2018–2021) prevalence of neonatal sepsis from the sample of 360 was 59%, with early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS) accounting for about 29% and 30%, respectively. These estimates translate to an average yearly prevalence of neonatal sepsis of 15%. Nonetheless, the disaggregated results as ...

  4. 4 days ago · Sepsis. Sepsis is a severe illness characterized by a systemic, whole-body response to infection and is a frequent cause of morbidity and mortality in hospitalized patients. Sepsis is most common in older individuals and infants, and can be difficult to diagnose due to its variable presentation. Because there is no confirmatory diagnostic test ...

  5. 5 days ago · The KSC is a validated tool that has been successfully utilized in many studies and is recommended as a potential EOS risk assess- ment tool along with categorical risk assessment and enhanced observation (2). As a result of the utilization of these approaches, there is a significant decrease in broad-spectrum antibiotic utiliza- tion, which decreases the separation of the mother-baby dyad ...

  6. 2 days ago · The study underscores the significance of histological fetal inflammatory response (FIR) in preterm infants born with histological chorioamnionitis (HCA), indicating its association with adverse neonatal outcomes such as early-onset sepsis (EOS), bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), and retinopathy of prematurity (ROP).

  7. 5 days ago · The article discusses several advancements in using AI to predict and manage sepsis, a life-threatening complication affecting millions globally. Recent developments include the TREWS system by Johns Hopkins University, which has shown promising results in early detection and treatment initiation across multiple hospitals. The University of California at San Diego has also developed the ...

  8. 2 days ago · Preterm infants, and EPT infants in particular, are highly susceptible to various infections, highlighting the immaturity of their immune system compared to that of full-term (FT) infants. 4, 5 For early-onset sepsis (< 72 h), representing vertical mother-to-infant transmission, Streptococcus agalactiae (GBS) and Escherichia coli are the most ...

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