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Prime VideoSubscriptionSubscriptionWatchApple TVSubscriptionSubscriptionWatchGoogle PlayRentalRental starting at $3.59WatchYouTubeRentalRental starting at $3.59WatchVUDURentalRental starting at $3.99WatchiTunesRentalRental starting at $3.99Watch18 hours ago · e. The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century. The scientific method involves careful observation coupled with rigorous scepticism, because cognitive assumptions can distort the interpretation of the observation.