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  1. Apr 25, 2024 · Among adults aged ≥50 years who were eligible to receive a second original monovalent mRNA COVID-19 vaccine booster dose, VE against COVID-19–associated emergency department and urgent care encounters during the SARS-CoV-2 Omicron BA.2/BA.2.12.1 period ≥120 days after the third dose was 32% but increased to 66% ≥7 days after the fourth ...

  2. Apr 19, 2024 · The bivalent booster, which is no longer available, was introduced in the fall of 2022. It targeted the BA.4 and BA.5 Omicron subvariants and the original SARS-CoV-2 virus. The updated vaccine is monovalent, designed to prevent severe disease from the Omicron XBB.1.5 subvariant.

    • 065208055
    • kathy.katella-cofrancesco@yale.edu
  3. Apr 15, 2024 · The vaccine candidates were monovalent mRNA-1273.815 (Omicron XBB.1.5) and bivalent mRNA-1273.231 (Omicron XBB.1.5 plus BA.4/BA.5), which were administered as third booster doses among a cohort of adults. Study patients were randomly assigned 1:1 to receive 50-µg doses of either the monovalent or bivalent vaccine candidate.

  4. 5 days ago · Data from vaccine manufacturers suggest that, for most people, vaccines and booster doses start protecting you against the coronavirus within a week or two after your injection. However, specific factors, discussed later, can play a role in how quickly you develop immunity against COVID-19.

  5. Apr 23, 2024 · COVID-19 Vaccines Are Safe, Effective, and Free. Everyone 6 months and older should get an updated COVID-19 vaccine. People aged 65 years and older who received 1 dose of any updated COVID-19 vaccine (Moderna, Pfizer-BioNTech or Novavax) should receive 1 additional dose of an updated COVID-19 vaccine at least 4 months after the previous updated ...

  6. Apr 18, 2024 · Here we conducted a multicenter open-label, randomized phase 2 and 3 study to assess the safety and immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron ...

  7. Apr 24, 2024 · New updated vaccines in September 2023 replaced the bivalent shots with ones targeting the XBB lineage of the Omicron variant. The original and bivalent vaccines are no longer in use, and it has yet to be decided whether updated shots will be administered annually, like the flu shot. Who can get it: People 6 months and older. The CDC has ...

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