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Feb 20, 2021 · Abstract. Thrombocytopenia, which signifies a low platelet count usually below 150 × 10 9 /L, is a common finding following or during many viral infections. In clinical medicine, mild thrombocytopenia, combined with lymphopenia in a patient with signs and symptoms of an infectious disease, raises the suspicion of a viral infection.
Dec 14, 2013 · Prophylactic platelet transfusions are given in dengue fever with thrombocytopenia to prevent hemorrhagic complications. Although the use of prophylactic platelet transfusions is increasing in countries where dengue is endemic, it is associated with risks and has financial implications. [ 2] The decision to transfuse platelets is based on ...
May 20, 2011 · A study was conducted to note the relationship between the platelet counts and severity of the disease in pediatric cases of dengue fever. Platelet counts were found to be predictive as well as recovery parameter of DF/DHF/DSS. Keywords: Dengue, Dengue haemorrhagic syndrome , Dengue shock syndrome, Platelet count, Thrombocytopenia.
Sep 29, 2023 · Dengue, a vector borne infection causes decline in platelet levels. If the platelet declines to extreme low levels, like 10,000/microlitre of blood, platelet transfusion is suggested. During platelet donations, platelets are separated from other components which are then given back into the donor. One must have a haemoglobin level equal to or ...
Dec 18, 2014 · Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis. While platelet activation and elevated platelet counts (thrombocytosis) are associated with increased risk of thrombotic complications, low platelet counts (thrombocytopenia) and several platelet function disorders increase the risk of bleeding.
Mar 7, 2018 · Platelets were mainly associated with coagulation and hemostasis; however, other biological effects have been attributed to platelets, including angiogenesis, extracellular matrix synthesis, inflammation, and immune response. Dengue virus infection causes 200 million cases of severe flu-like illness annually, escalating to life-threatening hemorrhagic fever or shock syndrome. Some hypotheses ...
A common symptom in more severe cases is thrombocytopenia or loss of platelets. Platelets are small blood cells that lack a nucleus and are important for blood clotting and immunity. Platelets from patients with dengue have been shown to contain virus-like particles; however the involvement of platelets in dengue virus infections is unclear.
