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   How is early onset neonatal sepsis treated?

   • The only intervention proven to decrease the incidence of early-onset neonatal sepsis is maternal treatment with intrapartum intravenous antimicrobial agents for the prevention of GBS infections. 93 Adequate prophylaxis is defined as penicillin (the preferred agent), ampicillin, or cefazolin given for ≥4 hours before delivery.

   Management of Neonates With Suspected or Proven Early-Onset Bacter…

   publications.aap.org/pediatrics/article/129/5/1006/73781/Management-of-Neonates-With-Suspected-or-Proven

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   How common is early onset neonatal sepsis?

   • Pediatrics (2012) 129 (5): 1006–1015. With improved obstetrical management and evidence-based use of intrapartum antimicrobial therapy, early-onset neonatal sepsis is becoming less frequent. However, early-onset sepsis remains one of the most common causes of neonatal morbidity and mortality in the preterm population.

   Management of Neonates With Suspected or Proven Early-Onset Bacter…

   publications.aap.org/pediatrics/article/129/5/1006/73781/Management-of-Neonates-With-Suspected-or-Proven

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   What is a clinicopathologic approach to neonatal sepsis?

   • Clinicopathologic approach to the diagnosis of neonatal sepsis. Volume of blood required to detect common neonatal pathogens. Neonatal Escherichia coli septicemia—bacterial counts in blood. Frequency of low level bacteremia in infants from birth to two months of age. Volume of blood submitted for culture from neonates.

   Management of Neonates With Suspected or Proven Early-Onset Bacter…

   publications.aap.org/pediatrics/article/129/5/1006/73781/Management-of-Neonates-With-Suspected-or-Proven

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2. publications.aap.org › pediatrics › articleClinical Practice Guideline: Evaluation and Management of ...

   publications.aap.org › pediatrics › article

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   Aug 1, 2021 · Copyright © 2021 by the American Academy of Pediatrics. This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted.

3. publications.aap.org › pediatricsinreview › articleEvaluation and Management of Young Febrile Infants: An ...

   publications.aap.org › pediatricsinreview › article

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   Mar 1, 2023 · The American Academy of Pediatrics released a clinical practice guideline for the management of febrile infants in August 2021 to compile nearly 40 years of research into a cohesive text that would provide a framework for the clinician in safely managing these patients in a variety of settings.