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Mar 15, 2010 · Physicians often have difficulty diagnosing a generalized rash because many different conditions produce similar rashes, and a single condition can result in different rashes with varied appearances.
- John W. Ely, Mary Seabury Stone
Acute Skin Problems; ... Morbilliform rash eventually spread to the face and extremities of the same child. ... Pictures and symptoms of the red, scaly rash. Skin Infections.
Mar 27, 2019 · Scott Camazine/Getty Images. ... It’s most commonly seen on the neck, chest, back, and arms. 6. Morbilliform Drug Eruption. ... In addition to the rash, symptoms may include fever or chills.
- Signs and symptoms
Morbilliform rash, or \\"measles-like\\" maculopapular skin eruption, is commonly caused by certain drug reactions or viral diseases. Maculopapular rashes are skin eruptions that exhibit both the characteristics of a macule and papule. Macules are small, circumscribed and discolored spots on the skin. The diameter of a macule is not more than .4 inches (10 mm). Papules, on the other hand, are eruptions on the skin, which can look something like a pimple. Morbilliform rashes, therefore, are raised, discolored spots that spread symmetrically across the body.
These rashes may occur due to bacterial infections, drug reactions, and specific or non-specific viral exanthems, also known as viral rashes. A viral exanthem is non-specific if there is no exact information on the virus that has caused the rash. In such a case, the clinician identifies the presence of the virus that is likely to have caused the rash. Morbilliform rash is a \\"late drug rash.\\" It appears on the skin of the affected individual after one to two weeks of exposure to drugs, such as antibiotics or barbiturates. Drug-caused rashes of this kind are usually associated with penicillin, cephalosporins, sulphonamides, and anticonvulsants. Morbilliform rashes often occur in children affected by viral diseases such as measles, Rubella, Roseola, and Erythema infectiosum. In adults, these rashes are usually non-specific viral rashes. This type of rash is also frequently seen in patients who administer ampicillin for the treatment of mononucleosis caused by Epstein-Barr virus or cytomegalovirus. People with human immunodeficiency virus (HIV) tend to develop an acute morbilliform rash when treated with sulfa drugs.
This rash can also appear as a consequence of certain viral diseases. If antibiotics have been started for the patient during the early stages of the viral disease, then the appearance of a morbilliform rash may lead to confusion in diagnosis. Once a drug-induced morbilliform rash is diagnosed, the doctor may ask the patient to discontinue the use of a particular drug.
Usually, oral antihistamines or topical corticosteroids are prescribed for treating these types of rashes. Oral corticosteroids are avoided, as there are chances of the rash to worsen during the steroid therapy, which may lead to the wrong diagnosis. A drug-induced morbilliform rash will usually subside within almost two weeks after the discontinuation of the particular drug. When this type of rash heals, the affected skin sheds or peels, which is also known as skin desquamation.
The patient with an acute maculopapular rash presents a diagnostic challenge to the clinician. The term 'maculopapular is non-specific, as many eruptions have a primary morphology of macules or papules, and the term may be misused to indicate any rash.
Mar 16, 2016 · The rash appears as small, pink pimple-like spots that appear in the stretch marks. They closely resemble hives. Eventually, the rash may start to come together and form large, red, plaque-like areas.
- Physical Examination
When the diagnosis of a generalized rash is not obvious, patients should be asked about recent travel, insect and plant exposure, drug exposure (including over-the-counter drugs, alternative medications, and illicit drugs), contact with persons who are ill, pets, hobbies, occupational exposures, chemical exposure, chronic illness, sexual history, and recent systemic symptoms, especially fever (Table 1). Patients should be asked about pruritus, painful lesions, the initial site of involvement,...
Characteristics of the rash itself can help narrow the differential diagnosis. In dermatologic diagnosis, it is often helpful to focus on the clinical appearance of the rash after determining the patient's primary symptom, but before taking a more focused history.6 This approach may not be intuitive to primary care physicians, who would normally take a complete history first and then perform a physical examination. The size of individual lesions can vary from pinpoint to total-body redness (i...
Blood tests that may be helpful include a complete blood count to determine the presence of leukocytosis or thrombocytopenia, and serologic studies to identify various infectious causes. Mineral oil mounts and potassium hydroxide scrapings can be helpful when scabies or dermatophytes are considered. Skin biopsy, with or without direct or indirect immunofluorescence, is often helpful, especially to confirm lichen planus, dermatitis herpetiformis, mycosis fungoides, and staphylococcal scalded s...
INTRODUCTION. Exanthematous drug eruption, also called morbilliform or maculopapular drug eruption, is the most common type of drug hypersensitivity reaction .They are characterized by a diffuse and symmetric eruption of erythematous macules or small papules occurring approximately one week or, in previously sensitized individuals, as early as one or two days after the initiation of drug ...
- What Is A Blistering Disease?
- Acute Blistering Diseases
- Chronic Blistering Diseases
A blistering disease is a condition in which there are fluid-filled skin lesions. 1. Vesicles are small blisters less than 5 mm in diameter. 2. A bulla is a larger blister. Note that the plural of bulla is bullae. 3. Blisters may break or the roof of the blister may become detached forming an erosion. Exudation of serous fluid forms crust.
Acute blistering diseases can be generalised or localised to one body site and are due to infection or inflammatory disorders. Although most commonly eczematous, generalised acute blistering diseases can be life-threatening and often necessitate hospitalisation. Acute blistering conditions should be investigated by taking swabs for bacterial and viral culture. A skin biopsy may be helpful in making a diagnosis.
Diagnosis of chronic blistering diseases often requires skin biopsy for histopathology and direct immunofluorescence. A blood test for specific antibodies (indirect immunofluorescence) may also prove helpful in making the diagnosis of an immunobullous disease.
Nov 27, 2018 · One of the symptoms is a rash, which appears in three stages: A blotchy red rash on the cheeks with groups of red papules. After 4 days, a net of red marks may appear on the arms and trunk.