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Alexander Fleming was a Scottish scientist who discovered the first antibiotic drug, penicillin. He shared the Nobel Prize for Medicine in 1945 with Howard Florey and Ernst Chain, who had also worked on developing penicillin as a drug.
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Sir Alexander Fleming was a Scottish physician and microbiologist best known for his discovery of penicillin, the world's first and widely effective antibiotic.
- Antiseptics
- Discovery of Lysozyme
- Discovery of Penicillin
During World War I, Fleming with Leonard Colebrook and Sir Almroth Wright joined the war efforts and practically moved the entire Inoculation Department of St Mary's to the British military hospital at Boulogne-sur-Mer. Serving as Temporary Lieutenant of the Royal Army Medical Corps, he witnessed the death of many soldiers from sepsis resulting fro...
At St Mary's Hospital, Fleming continued his investigations into bacteria culture and antibacterial substances. As his research scholar at the time V.D. Allison recalled, Fleming was not a tidy researcher and usually expected unusual bacterial growths in his culture plates. Fleming had teased Allison of his "excessive tidiness in the laboratory," a...
Experiment
By 1927, Fleming had been investigating the properties of staphylococci. He was already well known from his earlier work, and had developed a reputation as a brilliant researcher. In 1928, he studied the variation of Staphylococcus aureus grown under natural condition, after the work of Joseph Warwick Bigger, who discovered that the bacterium could grow into a variety of types (strains). On 3 September 1928, Fleming returned to his laboratory having spent a holiday with his family at Suffolk....
Reception and publication
Fleming presented his discovery on 13 February 1929 before the Medical Research Club. His talk on "A medium for the isolation of Pfeiffer's bacillus" did not receive any particular attention or comment. Henry Dale, the then Director of National Institute for Medical Research and chair of the meeting, much later reminisced that he did not even sense any striking point of importance in Fleming's speech. Fleming published his discovery in 1929 in the British Journal of Experimental Pathology,but...
Purification and stabilisation
In Oxford, Ernst Boris Chain and Edward Abraham were studying the molecular structure of the antibiotic. Abraham was the first to propose the correct structure of penicillin. Shortly after the team published its first results in 1940, Fleming telephoned Howard Florey, Chain's head of department, to say that he would be visiting within the next few days. When Chain heard that Fleming was coming, he remarked "Good God! I thought he was dead." Norman Heatley suggested transferring the active ing...
Fleming was studying deadly bacteria in 1928 when he made his dramatic discovery. Always retiring and modest, he attributed it to “the greatest fortune.” However, it was fortune combined with a gift for scientific observation and a genius for research.
Aug 2, 2023 · In this video, we learn all about Alexander Fleming and what he invented to earn himself a noble prize. Check out this fun PowerPoint all about Alexander Fle...
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If your child’s looking for information and facts about Alexander Fleming, then you’ve come to the right place. With his discovery of penicillin, Alexander Fleming is one of our most significant scientists. Read this blog to find out interesting activities and facts about Alexander Fleming.
Alexander Fleming discovered that a mold called <i>Penicillium notatum</i> stopped the growth of <i>Staphylococcus</i> bacteria. The bacteria causes illnesses, so the discovery led to the creation of drugs to cure the illnesses.
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