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  1. These are the most common symptoms of ALS: Twitching and cramping of muscles, especially those in the hands and feet. Loss of motor control in the hands and arms. Impairment in the use of the arms and legs. Tripping and falling. Dropping things. Persistent fatigue. Uncontrollable periods of laughing or crying.

  2. What are the symptoms of ALS? At first, you may notice muscle weakness or stiffness: Limb onset ALS is when the symptoms start in your legs or arms. For example, you may have hand weakness. Buttoning a shirt or writing might be difficult. Or you may notice leg symptoms. You may have trouble walking or frequently trip.

  3. Apr 10, 2024 · Early symptoms include: Muscle twitches in the arm, leg, shoulder, or tongue. Muscle cramps. Tight and stiff muscles (spasticity) Muscle weakness affecting an arm, a leg, or the neck. Slurred and nasal speech. Difficulty chewing or swallowing. As the disease progresses, muscle weakness and atrophy spread to other parts of your body.

  4. Home. Understanding ALS. What is ALS? ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. ”Amyotrophic” comes from the Greek language. "A" means no. "Myo" refers to muscle. "Trophic" means nourishment.

  5. Apr 10, 2024 · Amyotrophic lateral sclerosis, known as ALS, can be hard to diagnose early because it can have symptoms similar to other diseases. Tests to rule out other conditions or help diagnose ALS might include:

  6. Apr 12, 2024 · Symptoms and Diagnosis. ALS is a disease that typically involves a gradual onset. The initial symptoms of ALS can be quite varied. One person may have trouble grasping a pen or lifting a coffee cup, while another may experience a change in vocal pitch when speaking. The rate at which ALS progresses can be quite variable, as well.

  7. Print. Join the National ALS Registry. What is ALS? Many people know ALS as Lou Gehrigs disease, named after the famous baseball player who got the illness and had to retire in 1939 because of it. ALS is a disease that affects the nerve cells that make muscles work in both the upper and lower parts of the body.

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