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   Does donepezil help with Alzheimer's disease?

   • Although there is currently no evidence to suggest that donepezil can alter the progression of the disease, it has shown efficacy in alleviating specific symptoms by improving cognition and/or behavior in affected individuals. In addition to its FDA-approved use in Alzheimer disease, donepezil has various off-label indications.

   Donepezil - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK513257/

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   Does donepezil reduce delirium in critically ill dementia patients?

   • Lieberman OJ, Lee S, Zabinski J. Donepezil treatment is associated with improved outcomes in critically ill dementia patients via a reduction in delirium. Alzheimers Dement. 2023 May;19(5):1742-1751.

   Donepezil - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK513257/

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   Can donepezil help with Parkinson disease?

   • Dementia-associated with Parkinson disease: Certain evidence suggests that donepezil can be beneficial in improving cognition, executive function, and overall global status in individuals with dementia associated with Parkinson disease.

   Donepezil - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK513257/

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2. www.drugs.com › mtm › donepezilDonepezil Uses, Side Effects & Warnings - Drugs.com

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   Oct 26, 2023 · Donepezil dosing information. Usual Adult Dose for Alzheimer's Disease: Initial dose: 5 mg orally once a day, in the evening prior to retiring Mild to moderate Alzheimer's disease:-Maintenance dose: 10 mg orally once a day, after the patient has been on an initial dose of 5 mg once a day for 4 to 6 weeks Moderate to severe Alzheimer's disease:

   • 5.3/10 (117)

3. www.alz.org › treatments › medications-for-memoryMedications for Memory Loss | Alzheimer's Association

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   The cholinesterase inhibitors most commonly prescribed are: Donepezil (Aricept®): approved to treat all stages of Alzheimer’s disease. Rivastigmine (Exelon®): approved for mild-to-moderate Alzheimer’s as well as mild-to-moderate dementia associated with Parkinson’s disease. Galantamine (Razadyne®): approved for mild-to-moderate stages ...

4. my.clevelandclinic.org › health › drugsDonepezil (Aricept): Uses & Side Effects - Cleveland Clinic

   my.clevelandclinic.org › health › drugs

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   Donepezil is a medication that treats symptoms of Alzheimer’s disease like memory loss and confusion. This medication works by improving your attention, memory and ability to engage in your daily activities. It isn’t a cure for Alzheimer’s disease or dementia. The brand name of this medication is Aricept®.

5. www.mayoclinic.org › alzheimers › art-20048103How Alzheimer's medicines help manage symptoms - Mayo Clinic

   www.mayoclinic.org › alzheimers › art-20048103

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   Apr 11, 2024 · Brexpiprazole (Rexulti) is a kind of medicine called an atypical antipsychotic. The FDA approved brexpiprazole for treating agitation linked to dementia due to Alzheimer's disease. The medicine is taken as a pill once a day. The label for brexpiprazole carries a severe warning.

   • Role of Current Alzheimer's Drugs

     The Food and Drug Administration (FDA) has approved two types of drugs specifically to treat symptoms of Alzheimer's disease. 1. Cholinesterase inh...
   • Cholinesterase Inhibitors

     One way Alzheimer's disease harms the brain is by decreasing levels of a chemical messenger (acetylcholine) that's important for alertness, memory,...
   • Memantine For Later Stages

     Memantine (Namenda) is approved by the FDA for treatment of moderate to severe Alzheimer's disease. It works by regulating the activity of glutamat...
   • When to Discontinue Alzheimer's Drugs

     Because Alzheimer's is a progressive disease, your symptoms and care plan will change over time. If you're taking an Alzheimer's drug, ongoing revi...

6. www.ncbi.nlm.nih.gov › pmc › articlesDonepezil for dementia due to Alzheimer's disease - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 18, 2018 · Donepezil was also associated with better function measured with the Alzheimer's Disease Cooperative Study activities of daily living score for severe Alzheimer's disease (ADCS‐ADL‐sev) (MD 1.03, 95% CI 0.21 to 1.85, 733 participants, 3 studies).

   • Author: Jacqueline S Birks, Richard J Harvey
   • DOI: 10.1002/14651858.CD001190.pub3

   • Publish Year: 2006
   • Published: 2018

7. medlineplus.gov › druginfo › medsDonepezil: MedlinePlus Drug Information

   medlineplus.gov › druginfo › meds

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   Donepezil is in a class of medications called cholinesterase inhibitors. It improves mental function (such as memory, attention, the ability to interact with others, speak, think clearly, and perform regular daily activities) by increasing the amount of a certain naturally occurring substance in the brain. Donepezil may improve the ability to ...

8. www.ncbi.nlm.nih.gov › books › NBK513257Donepezil - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK513257

   Aug 17, 2023 · Donepezil hydrochloride, a piperidine derivative, is a centrally acting, rapid, and reversible acetylcholinesterase inhibitor primarily utilized for treating Alzheimer disease. Acetylcholinesterase is an enzyme that breaks down acetylcholine after its release from the presynapse. By binding reversibly to acetylcholinesterase, donepezil inhibits acetylcholine hydrolysis, thereby increasing ...