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Apr 30, 2024 · Admire the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians. Be treated to southern hospitality and historic charm at every port. Come explore the Mississippi with America’s #1 river cruise line.
- New Orleans Round-Trip
Historic Mississippi River Cruise. New Orleans, LA to New...
- Lower Mississippi
Lower Mississippi River Cruise. Memphis, TN to New Orleans,...
- Grand Heartland
Aboard the authentic La Crosse Queen paddle-wheeler, cruise...
- Columbia & Snake River Cruises
Follow the footsteps of the epic Lewis and Clark Expedition...
- Puget Sound Cruises
American Cruise Lines offers acapella-style groups, a lively...
- New Orleans Round-Trip
Cruise Overview. Sail 1,393 miles, through 10 states, on the most comprehensive exploration of the Mighty Mississippi available. This epic cruise showcases the culture and cuisine of the historic South, and the rolling farmlands of the Midwest as we explore the entire length of this legendary river. We embrace the relaxed pace of life on the ...
Enjoy our 9-day Upper Mississippi River Cruise from St. Louis to St. Paul. Tour Mark Twain's Hometown, Black Hawk State Park & other Historic Landmarks.
800-460-4518. Ready to plan your Mississippi River Cruise? Find out how to pack for your river cruise, the best time to cruise the Mississippi River, fun facts, and more.
America's Most Awarded River Cruise Line. American Cruise Lines offers 50+ US River Cruises along the Mississippi, Columbia & Snake Rivers, New England & Alaska Waterways on luxurious Small Cruise Ships.