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  1. Feb 10, 2023 · The standard treatment for Lyme disease is an antibiotic taken as a pill. The treatment usually lasts 10 to 14 days. Treatment may be longer depending on your symptoms.

  2. Sep 13, 2022 · In lieu of doxycycline, children under age 8 may be prescribed amoxicillin based on body weight (50 mg/kg/day every eight hours). Cephalosporins like cefuroxime axetil and cefdinir are also possible choices for young children, taken twice a day, based on weight (125 to 500 mg every 12 hours).

  3. The three first-line oral antibiotics for Lyme disease include doxycycline (Monodox, Doryx, Vibramycin, Oracea), amoxicillin (Amoxil), and cefuroxime (Ceftin, Zinacef). Ceftriaxone (“Rocephin”) administered intravenously is the preferred antibiotic for neurologic Lyme disease in the United States.

  4. The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the second generation cephalosporin, Ceftin.

  5. For early Lyme disease, a short course of oral antibiotics, such as doxycycline or amoxicillin, cures the majority of cases. In more complicated cases, Lyme disease can usually be successfully treated with three to four weeks of antibiotic therapy.

  6. Guidelines for Antibiotic Treatment of Lyme Disease in Adults*. Drug. Dosage. Early Lyme disease†. 500 mg orally 3 times a day for 14 days. 100 mg orally twice a day for 10 days. 500 mg orally twice a day for 14 days. 500 mg orally once a day for 7 days. Neurologic manifestations.

  7. Oct 25, 2023 · Early localized Lyme disease — Early localized Lyme disease (the erythema migrans rash, with or without flu-like symptoms) is treated with oral antibiotics, usually doxycycline, amoxicillin, or cefuroxime, taken daily. Doxycycline is given for 10 to 21 days, and amoxicillin and cefuroxime are given for 14 to 21 days.

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