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  1. Jul 13, 2017 · References. Amyotrophic lateral sclerosis (ALS) is a progressive, paralytic disorder characterized by degeneration of motor neurons in the brain and spinal cord. It begins insidiously with focal ...

  2. Jan 17, 2024 · Amyotrophic lateral sclerosis (ALS) is a group of progressive diseases that affect the nerve cells in the brain and spinal cord that control muscle movement. People with ALS will gradually lose ...

  3. Amyotrophic lateral sclerosis (ALS) is a progressive disease that affects motor neurons, which are specialized nerve cells that control muscle movement. These nerve cells are found in the spinal cord and the brain. In ALS, motor neurons die (atrophy) over time, leading to muscle weakness, a loss of muscle mass, and an inability to control movement.

  4. A gradual onset of progressive muscle weakness – which is generally painless – is the most common initial symptom of ALS. Other early symptoms vary but can include tripping, dropping things, abnormal fatigue of the arms and/or legs, slurred speech, muscle cramps and twitches and uncontrollable periods of laughing or crying.

  5. Amyotrophic. lateral sclerosis (ALS) is a rare neurological disease that afects nerve cells (neurons) in the brain and spinal cord that control voluntary muscle movement. Voluntary muscles produce movements like chewing, walking, breathing and talking. The disease is progressive, meaning the symptoms get worse over time.

  6. Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease (MND). MNDs may involve the central nervous system (CNS) as well as the peripheral nervous system. Usually, etiology is unknown. However, approximately 15% of cases are hereditary; they result from mutations in the superoxide dismutase (SOD) 1 gene (1). Nomenclature and ...

  7. Mar 15, 2023 · Amyotrophic lateral sclerosis (ALS) causes a slow degeneration of nerve cells (called motor neurons) that control muscle movements. As a result, people with ALS gradually lose the ability to control their muscles. Fortunately, their capacity to think and remember things usually is not affected.

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