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Arsenic trioxide is an inorganic compound with the formula As 2 O 3. As an industrial chemical, its major uses include the manufacture of wood preservatives, pesticides, and glass. It is sold under the brand name Trisenox among others when used as a medication to treat a type of cancer known as acute promyelocytic leukemia.
- As₂O₃
- Trisenox, others
- AU: X (High risk)
- Intravenous
What is arsenic trioxide? Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide.
- What Is Arsenic trioxide?Arsenic trioxide is a cancer medication that interferes with the growth and spread of cancer cells in the body.Arsenic trioxide is used to treat a...
- Before Taking This MedicineYou should not be treated with arsenic trioxide if you are allergic to it.Tell your doctor if you have ever had: 1. heart problems, or a heart rhyt...
- How Is Arsenic Trioxide given?Arsenic trioxide is given as an infusion into a vein. A healthcare provider will give you this injection.You may need frequent medical tests to be...
- What Should I Avoid While Receiving Arsenic trioxide?This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to c...
- Arsenic Trioxide Side EffectsGet emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Ar...
- Arsenic Trioxide Dosing InformationUsual Adult Dose for Acute Promyelocytic Leukemia:-Induction: IV infusion of 0.15 mg/kg over 1 to 2 hours once a day until bone marrow remission.Ma...
- What Other Drugs Will Affect Arsenic trioxide?Arsenic trioxide can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart p...
It is used: In adults with newly diagnosed APL that is low risk. In patients whose cancer has not gotten better or has relapsed after retinoid and anthracycline chemotherapy. Arsenic trioxide is also being studied in the treatment of other types of cancer.
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This medical management guide focuses specifically on arsenic trioxide (an arsenite), which is one of the most toxic forms of arsenic. As little as 1–2.5 mg/kg of arsenic trioxide is a potentially fatal dose.
Arsenic trioxide is a chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.
May 1, 2024 · Arsenic trioxide belongs to the general group of medicines called antineoplastics. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by arsenic trioxide, other unwanted effects will also occur.
Oct 6, 2021 · In the 1970s, arsenic trioxide, the active ingredient in a traditional Chinese medicine, was shown to produce dramatic remission of acute promyelocytic leukemia similar to the effect of all-trans retinoic acid. Since then, there has been a renewed interest in the clinical use of arsenicals.
