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Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Macrolides belong to the polyketide class of natural products. Some macrolides have antibiotic or antifungal ...
After significant safety concerns, the US Food and Drug Administration sharply curtailed the approved uses of the drug in early 2007. Telithromycin is a semi-synthetic erythromycin derivative. It is created by substituting a ketogroup for the cladinose sugar and adding a carbamate ring in the lactone ring.
Apr 24, 2024 · Find patient medical information for Azithromycin – Uses, Side Effects, and More on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings
Azalide. Azalides such as azithromycin are a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides ( erythromycin ). [1] Following the clinical overuse of macrolides and azalides, ketolides have been developed to combat surfacing macrolide-azalide resistance ...
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of a number of bacterial infections. This includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infe
Jul 29, 2021 · Azithromycin. Trade Names: Zithromax ®. Drug Class: Macrolide antibiotic. Mechanism of Action: same as clarithromycin. Indications: same as clarithromycin. Contraindications: less likely to affect the QT interval vs. clarithromycin or erythromycin.
Clarithromycin was developed in 1980 and approved for medical use in 1990. [4] [5] It is on the World Health Organization's List of Essential Medicines. [6] Clarithromycin is available as a generic medication. [3] It is made from erythromycin and is chemically known as 6-O-methylerythromycin.
