Escherichia noobie coli (/ ˌ ɛ ʃ ə ˈ r ɪ k i ə ˈ k oʊ l aɪ /), also known as E. coli (/ ˌ iː ˈ k oʊ l aɪ /), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
Escherichia coli (Latin pronunciation: [eskeˈrikja ˈkoli] Anglicized to / ˌɛʃəˈrɪkiə ˈkoʊlaɪ /; commonly abbreviated E. coli) is a gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
Escherichia coli or E. coli is a bacterium that can be found in human intestines. Scientists have studied E. coli a lot, and know more about how E. coli cells work than any other organism. E. coli is not always harmful. In fact, the only known harmful strand is O157.
- Signs and symptoms
Escherichia coli O157:H7 is a serotype of the bacterial species Escherichia coli and is one of the Shiga-like toxin–producing types of E. coli. It is a cause of disease, typically foodborne illness, through consumption of contaminated and raw food, including raw milk and undercooked ground beef. Infection with this type of pathogenic bacteria may lead to hemorrhagic diarrhea, and to kidney failure; these have been reported to cause the deaths of children younger than five years of age, of...
E. coli O157:H7 infection often causes severe, acute hemorrhagic diarrhea and abdominal cramps. Usually little or no fever is present, and the illness resolves in 5 to 10 days. It can also sometimes be asymptomatic. In some people, particularly children under five years of age, persons whose immunologies are otherwise compromised, and the elderly, the infection can cause hemolytic uremic syndrome, in which the red blood cells are destroyed and the kidneys fail. About 2–7% of infections ...
Like the other strains of the species, O157:H7 is gram-negative and oxidase-negative. Unlike many other strains, it does not ferment sorbitol, which provides a basis for clinical laboratory differentiation of the strain. Strains of E. coli that express Shiga and Shiga-like toxins gained that ability via infection with a prophage containing the structural gene coding for the toxin, and nonproducing strains may become infected and produce shiga-like toxins after incubation with shiga toxin positiv
Infection with E. coli O157:H7 can come from ingestion of contaminated food or water, or oral contact with contaminated surfaces. Examples of this can be undercooked ground beef but also leafy vegetables and raw milk. Fields often get contaminated with the bacterium through irrigation processes or contaminated water naturally entering the soil. It is highly virulent, with a low infectious dose: an inoculation of fewer than 10 to 100 CFU of E. coli O157:H7 is sufficient to cause infection, compar
A stool culture can detect the bacterium, although it is not a routine test and so must be specifically requested. The sample is cultured on sorbitol-MacConkey agar, or the variant cefixime potassium tellurite sorbitol-MacConkey agar. On SMAC agar, O157:H7 colonies appear clear due to their inability to ferment sorbitol, while the colonies of the usual sorbitol-fermenting serotypes of E. coli appear red. Sorbitol nonfermenting colonies are tested for the somatic O157 antigen before being confirm
E. coli O157:H7 infection is nationally reportable disease in the US, Great Britain, and Germany, and most US states. It is also reportable in most states of Australia including Queensland.
Escherichia coli Coliform bacteria are defined as Rod shaped Gram-negative non- spore forming and motile or non-motile bacteria which can ferment lactose with the production of acid and gas when incubated at 35–37°C.
(Inggris) E. coli Statistics (Inggris) E. coli computational and real Models Diarsipkan 2008-10-04 di Wayback Machine. (Inggris) Scientists engineer bacteria to create living photographs (Inggris) Scientists are synthetically engineering E. coli that can target and kill cancer cells (Inggris) 2006 Recent Stories
This is achievable in some well-studied bacteria, with models of Escherichia coli metabolism now being produced and tested.   This understanding of bacterial metabolism and genetics allows the use of biotechnology to bioengineer bacteria for the production of therapeutic proteins, such as insulin , growth factors , or antibodies .
For instance, in E. coli, 70S ribosomes form 90S dimers upon binding with a small 6.5 kDa protein, ribosome modulation factor RMF.   These intermediate ribosome dimers can subsequently bind a hibernation promotion factor (the 10.8 kDa protein, HPF) molecule to form a mature 100S ribosomal particle, in which the dimerization interface is ...
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