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Feb 19, 2022 · A recent study evaluated the efficacy of four treatments (5% imiquimod cream, methyl aminolevulinate PDT [MAL-PDT], 5% 5-FU cream, and 0.015% ingenol mebutate gel [IGM]) for AK located on the head and neck. Results showed that 5% 5-FU cream was the most effective among the field-directed treatments.
- 10.1007/s40257-022-00674-3
- 2022
- Am J Clin Dermatol. 2022; 23(3): 339-352.
Jul 7, 2022 · Cryotherapy is the most commonly used lesion-targeted, destructive treatment, in which liquid nitrogen is applied to the lesion using a spray or cotton swab [ 2 ]. Cryotherapy is easy to implement and has the advantage of not having to rely on the patient’s compliance in the treatment process.
- 10.3390/jcm11143953
- 2022/07
- J Clin Med. 2022 Jul; 11(14): 3953.
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Strong recommendations are made for using ultraviolet protection, topical imiquimod, topical 5-fluorouracil, and cryosurgery. Conditional recommendations are made for the use of photodynamic therapy and diclofenac for the treatment of AK, both individually and as part of combination therapy regimens.
- Daniel B. Eisen, Maryam M. Asgari, Daniel D. Bennett, Suzanne M. Connolly, Robert P. Dellavalle, Est...
- 2021
Mar 24, 2021 · Calcipotriol 0.005% and 5% 5-FU combination cream (usually mixed via compounding pharmacies in a 1:1 ratio) is applied twice daily for 4 days as field treatment for actinic keratoses. Dr. Hanke usually sees patients at this 4-day time period and determines the degree of inflammation.
Mar 13, 2019 · At 12 months after the end of treatment, 5% fluorouracil cream was the most effective treatment. The following NEJM Journal Watch summary explains the study: Treating Actinic Keratosis:...
Treatment options for AK include field-directed therapies, such as topical medications and photodynamic therapy, and lesion-directed therapies, like cryosurgery and laser ablation. Analysis of the evidence from a systematic review based on five research questions resulted in eighteen evidence-based recommendations and suggests there are several ...
Mar 15, 2024 · Treatment modalities range from cryotherapy for individual lesions to photodynamic therapy and topical agents like 5-fluorouracil and imiquimod for field damage. 7 Choices are based on the site and type of lesion, patient preference and access to treatment modalities. Etiopathogenesis.
