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  1. www.ncbi.nlm.nih.gov › pmc › articlesTreatment of Actinic Keratosis: The Best Choice through an...

    Jul 7, 2022 · Actinic keratosis (AK) is a precancerous lesion that can progress to invasive squamous cell carcinoma if untreated. However, no gold standard treatment has been established. We aimed to investigate the management of AK by comparing the effectiveness and treatment duration of treatment modalities, including cryotherapy, imiquimod (IMQ), and ...

    • 10.3390/jcm11143953
    • 2022/07
    • J Clin Med. 2022 Jul; 11(14): 3953.

  2. www.nejm.org › doi › fullRandomized Trial of Four Treatment Approaches for Actinic ...

    Mar 6, 2019 · With a prevalence of 37.5% among whites 50 years of age or older, actinic keratosis is one of the most frequent reasons for patients to visit a dermatologist. 1-3 If left untreated, actinic ...

    • Maud H E Jansen, Janneke P H M Kessels, Patty J Nelemans, Nina Kouloubis, Aimee H M M Arits, Han P A...
    • 2019

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  4. www.ncbi.nlm.nih.gov › pmc › articlesA Review of Existing Therapies for Actinic Keratosis: Current ...

    Feb 19, 2022 · Actinic keratosis (AK) is a chronic skin disease in which clinical and subclinical cutaneous lesions coexist on sun-exposed areas such as the head and neck region and the extremities. The high prevalence of AK means the disease burden is substantial, especially in middle-aged and elderly populations. Evidence indicates that AK may progress into ...

    • 10.1007/s40257-022-00674-3
    • 2022
    • Am J Clin Dermatol. 2022; 23(3): 339-352.

  5. nextstepsinderm.com › derm-topics › actinicActinic Keratoses: Evidence-Based Treatment Options

    Mar 24, 2021 · Clinical Pearl. Calcipotriol 0.005% and 5% 5-FU combination cream (usually mixed via compounding pharmacies in a 1:1 ratio) is applied twice daily for 4 days as field treatment for actinic keratoses. Dr. Hanke usually sees patients at this 4-day time period and determines the degree of inflammation. If it is sufficient, he stops, if the ...

  6. www.jaad.org › article › S0190-9622(21)00502-8Guidelines of care for the management of actinic keratosis

    Sponsored research funding or investigator-initiated studies with partial/full funding from pharmaceutical companies on actinic keratosis or actinic keratosis drugs in development or FDA approved If a potential conflict was noted, the Work Group member recused themselves from the discussion and drafting of recommendations pertinent to the topic ...

    • Daniel B. Eisen, Maryam M. Asgari, Daniel D. Bennett, Suzanne M. Connolly, Robert P. Dellavalle, Est...
    • 2021

  7. www.jaad.org › article › S0190-9622(21)00502-8Guidelines of care for the management of actinic keratosis

    Conclusions: Strong recommendations are made for using ultraviolet protection, topical imiquimod, topical 5-fluorouracil, and cryosurgery. Conditional recommendations are made for the use of photody-namic therapy and diclofenac for the treatment of AK, both individually and as part of combination therapy regimens.

  8. resident360.nejm.org › from-pages-to-practice › whatWhat’s the Best Treatment for Actinic Keratosis? | NEJM ...

    Mar 13, 2019 · What’s the best treatment for Paul? Actinic keratosis is one of the most common premalignant skin diseases, with a prevalence of 37.5% in white patients aged 50 years and older. Available treatments include cryotherapy for solitary lesions, phototherapy, and topical medications (e.g., fluorouracil cream). However, the guidelines are not clear ...