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  1. Dr. Bruce Ames is devoted to identifying strategies that combat degenerative disease and reverse aging processes. Best known for his groundbreaking research on mitochondria, the UC Berkeley professor emeritus discusses his innovative Triage Theory of Aging. Scientifically reviewed by Dr. Gary Gonzalez, MD, in August 2023.

  2. Jan 25, 2019 · Ames: Mitochondria are self-replicating organelles in the cell and are critical for producing ATP, the high-energy molecule in cells, which supports all metabolic functions requiring energy. Aging mitochondria become progressively inefficient in this process.

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    • Triage Theory
    • The Survival Vitamins
    • The Longevity “Vitamins”
    • The Catch

    Ames can confidently claim that 41 vitamins and minerals can ensure healthy aging because of “Triage Theory,” a hypothesis he described in a 2006 PNAS study. It states that when the body runs low on a certain vitamin or mineral, it’s forced to make a decision about how to use its meager supply: Should it be used to fix immediate issues, or should i...

    Of the 41 items on his list, Ames says there are ten items that are most often implicated when the body has to choose between short-term and long-term health. He points out his list is based on analysis and interpretation of other studies, noting that not all of these can be taken in a pill. He calls the following five “survival vitamins” because t...

    The remaining five on the list are a bit more obscure. His interpretation of existing research, he says, suggests these may have “anti-aging” effects. Like the survival vitamins, some of these can’t be taken in a pill, though Ames thinks that could change in the future. Ergothioneine: This is an amino acid that’s found all over the natural world. A...

    Ames doesn’t actually take all 41 substances himself because he doesn’t have to. That’s because there’s a far better way to consume all the substances on his list without buying a vitamin company. “If you are eating a well-balanced diet you are already consuming dozens of vitamins and minerals (and hundreds of other dietary bioactive components) at...

  4. Mar 1, 2022 · Professor Bruce Ames demonstrated that nutritional recommendations should be adjusted in order to ‘tune-up’ metabolism and reduce mitochondria decay, a hallmark of aging and many disease processes.

  5. Mar 27, 2019 · Mitochondria produce energy by breaking down food, explains Bruce H. Cohen, MD, a neurologist at Northeast Ohio Medical University and an expert in mitochondrial disease. Then they release that energy in the form of ATP, along with some byproducts, like carbon dioxide, water, and free radicals.

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  6. PMID: 35218912. DOI: 10.1016/j.freeradbiomed.2022.02.022. Abstract. Professor Bruce Ames demonstrated that nutritional recommendations should be adjusted in order to 'tune-up' metabolism and reduce mitochondria decay, a hallmark of aging and many disease processes.

  7. In the late 1990s, Dr. Bruce Ames and colleagues at the University of California, Berkeley began examining the effects of combining R-Lipoic Acid and Acetyl-L-Carnitine. 1 The research showed that the R form is more effective at promoting energy production, chelating metals, preventing cataract formation, and increasing glucose uptake into cells.

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