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1. www.uptodate.com › contents › exanthematousExanthematous (maculopapular) drug eruption - UpToDate

   www.uptodate.com › contents › exanthematous

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   Jan 12, 2023 · Cutaneous adverse events of molecularly targeted therapy and other biologic agents used for cancer therapy; Drug allergy: Pathogenesis; Drug hypersensitivity: Classification and clinical features; Drug reaction with eosinophilia and systemic symptoms (DRESS) Fixed drug eruption; Hand-foot skin reaction induced by multitargeted tyrosine kinase ...

   • Rosamaria Corona, Md, DSc

     Rosamaria Corona, Md, DSc - Exanthematous (maculopapular)...

   • Bigby M. Rates of Cutaneous Reactions to Drugs. Arch Dermatol 2001; 137:765

     43 PubMed | TI Effects of treatments on the mortality of...

   • Seitz Cs, Rose C, Kerstan A, Trautmann A. Drug-induced Exanthems: Correlation of Allergy Testing With Histologic Diagnosis. J Am Acad Dermatol 2013; 69:721

     Their biopsy specimens were retrospectively re-evaluated by...

2. www.ncbi.nlm.nih.gov › pmc › articlesHistopathology of drug eruptions – general criteria, common ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 31, 2011 · This does not distinguish drug eruptions from any other skin disease, and the reliability of histopathologic diagnosis of a drug eruption is not smaller than that of diseases for which biopsy is recommended without reservation, be it lichen planus, lupus erythematosus, or granuloma annulare.

   • Author: Wolfgang Weyers, Dieter Metze
   • DOI: 10.5826/dpc.0101a09

   • Publish Year: 2001
   • Published: 2011/01

3. www.dermatologyadvisor.com › home › decision-supportMorbilliform Drug Eruptions (exanthematous drug eruption ...

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   Mar 13, 2019 · Often, however, these patients have been on multiple drugs, which complicate the clinical picture. The presence of symptoms and signs that suggest GVHD, such as diarrhea, and liver function abnormalities should be looked for. Skin biopsy may be helpful in that acute GVHD may manifest satellite cell necrosis. However, this is not always seen.

4. emedicine.medscape.com › article › 1049474-workupDrug Eruptions Workup: Laboratory Studies, Imaging Studies ...

   emedicine.medscape.com › article › 1049474-workup

   Jul 7, 2022 · Biopsy can be helpful in confirming the diagnosis of a drug eruption (eg, by showing eosinophils in morbilliform eruptions or numerous neutrophils without vasculitis in persons with Sweet...

5. www.ncbi.nlm.nih.gov › pmc › articlesAnticancer Drugs Induced Severe Adverse Cutaneous Drug ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 17, 2018 · Anticancer drugs, including chemotherapy, target therapy, and recent immunotherapy causing skin reactions ranging from mild skin rash to life-threatening severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) with increase morbidity and mortality while they are receiving cancer ...

   • Author: Chau Yee Ng, Chun-Bing Chen, Ming-Ying Wu, Ming-Ying Wu, Jennifer Wu, Jennifer Wu, Chih-Hsun Yang, R...

   • Publish Year: 2018

6. www.nejm.org › doi › fullExanthematous Drug Eruptions | New England Journal of Medicine

   www.nejm.org › doi › full

   Jun 28, 2012 · Skin biopsy may help identify SJS–TEN or AGEP in their early phases, but specific histopathological features that would distinguish exanthematous eruptions from DRESS and viral exanthems...

7. People also ask

   What does a morbilliform rash look like?

   • The term “morbilliform” connotes a measles-like: the rash of measles is classically described as having macules that are 3 to 4 mm in size that coalesce. MDE is usually itchy. The eruption usually begins on the trunk and upper extremities and progresses caudally. It is usually symmetric.

   Morbilliform Drug Eruptions (exanthematous drug eruption; maculopapular

   www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/morbilliform-drug-eruptions-exanthematous-drug-eruption-maculopapular-drug-eruption-drug-rash/

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   Can a drug eruption be biopsied?

   • As a consequence, drug eruptions, with the exception of fixed drug eruption, are biopsied rarely on palms and soles. The same is true for the face and scalp. Hence, when one sees a biopsy specimen from face, scalp, or palmar and plantar surfaces, a drug eruption is unlikely.

   Histopathology of drug eruptions – general criteria, common patterns, a…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC3881081/

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   What is the role of biopsy in the diagnosis of drug eruptions?

   • Biopsy can be helpful in confirming the diagnosis of a drug eruption (eg, by showing eosinophils in morbilliform eruptions or numerous neutrophils without vasculitis in persons with Sweet syndrome). Drug eruptions are associated with a wide range of histologic findings, and immunomodulating medications can alter the histologic picture. [ 51]

   Drug Eruptions Workup: Laboratory Studies, Imaging Studies, Other Tes…

   emedicine.medscape.com/article/1049474-workup

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8. www.ccjm.org › content › 90/6/373Deadly drug rashes: Early recognition and multidisciplinary ...

   www.ccjm.org › content › 90/6/373

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   Jun 1, 2023 · Morbilliform drug rash, also called exanthematous or maculopapular drug eruption, is the most common, classically presenting with an erythematous maculopapular rash 1 to 2 weeks after a drug exposure. Urticarial rash, the second most common, presents as annular, pruritic, migratory plaques usually within hours of initial drug exposure. 2.