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  1. Sep 25, 2023 · 1. Heart disease. Number of deaths per year: 695,547. Percent of total deaths: 20 percent. More common among: men. people who smoke. people who are overweight or obese. people with a family history...

  2. Oct 6, 2023 · The Centers for Disease Control and Prevention (CDC) reports that 3.46 million people died in the US in 2021. Overall, 10 causes accounted for 74.5% of deaths that year. For comparison, the top 10 causes in 1999 accounted for approximately 80% of all deaths. Have deaths increased over time?

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  3. Dec 18, 2023 · The most common causes of death in the U.S. are heart disease and cancer, however, COVID-19 accounted for around 12 percent of all deaths that year, making it the third leading cause of...

    • Heart Disease. Number of deaths: 695,547. Rate: 173.8 per 100,000 population. Heart disease remained the top killer in the U.S. in 2021, accounting for about 20% of deaths even as its toll ticked down year over year by about 1,400 deaths.
    • Cancer. Number of deaths: 605,213. Rate: 146.6 per 100,000 population. The total number of cancer deaths in the U.S. increased by 2,863 in 2021, while the cancer death rate ticked up from 144.1 per 100,000 population in 2020.
    • COVID-19. Number of deaths: 416,893. Rate: 104.1 per 100,000 population. COVID-19 was the third-leading cause of death in the U.S. in 2021, surpassing the fourth-leading cause – unintentional injuries – by more than 190,000 deaths, as well as its 2020 toll by more than 66,000 deaths.
    • Accidents/Unintentional Injuries. Number of deaths: 224,935. Rate: 64.7 per 100,000 population. Unintentional injuries resulting from things like drug overdoses, car accidents and falls accounted for 6.5% of U.S. deaths in 2021.
  4. The age-adjusted death rate increased by 5.3% from 835.4 deaths per 100,000 standard population in 2020 to 879.7 in 2021. Age-specific death rates increased from 2020 to 2021 for each age group 1 year and over. Nine of the 10 leading causes of death in 2021 remained the same as in 2020.

  5. Jan 25, 2023 · Cardiovascular disease includes heart disease, stroke, heart failure and hypertension, or high blood pressure. Heart disease remains the leading cause of death in the U.S. and globally. In 2020, COVID-19 also appeared among the leading causes of death in the U.S.

  6. Apr 22, 2022 · COVID-19 Was Third Leading Cause of Death in U.S. CDC reports examine U.S. Death Rates for 2021. Media Statement. For Immediate Release: Friday, April 22, 2022. Contact: Media Relations. (404) 639-3286.

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