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  1. Data are for the U.S. Number of deaths for leading causes of death. Heart disease: 695,547. Cancer: 605,213. COVID-19: 416,893. Accidents (unintentional injuries): 224,935. Stroke (cerebrovascular diseases): 162,890. Chronic lower respiratory diseases: 142,342. Alzheimer’s disease: 119,399. Diabetes: 103,294.

  2. Oct 6, 2023 · The Centers for Disease Control and Prevention (CDC) reports that 3.46 million people died in the US in 2021. Overall, 10 causes accounted for 74.5% of deaths that year. For comparison, the top 10 causes in 1999 accounted for approximately 80% of all deaths. Have deaths increased over time?

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  3. The Table also presents leading causes of death in the US for the years 2015 to 2020. 4 According to provisional data, in 2020, there were notable changes in the number and ranking of deaths compared with 2019. 5 COVID-19 was the third leading cause of death in 2020, with an estimated 345 323 deaths, and was largely responsible for the ...

    • Farida B Ahmad, Robert N Anderson
    • 2021
  4. Age-specific death rates increased from 2020 to 2021 for each age group 1 year and over. Nine of the 10 leading causes of death in 2021 remained the same as in 2020. Heart disease, cancer, and COVID-19 remained the top 3 leading causes.

  5. In 2020, heart disease and cancer were the leading causes of death in the US, accounting for 1.29 million deaths, followed by COVID-19, accounting for 350 000 deaths. 1 - 3 The pandemic may also have indirectly led to increases in other causes of death, including heart disease, diabetes, Alzheimer disease, and unintentional injuries. 2, 4 We exa...

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