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  1. Jan 16, 2021 · Janeway lesions are irregular, painless, erythematous or haemorrhagic macules, or papules commonly found on the palms and soles. The pathogenesis of Janeway lesions is still a controversial topic in the literature, but the main hypothesis is based on septic embolic events. Although current diagnosis of endocarditis is unlikely to be made only ...

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    • Outlook / Prognosis
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    Liver lesions are abnormal growths that occur for a variety of reasons. Some are noncancerous (benign), and others are cancerous. Many benign lesions do not need treatment. But if it’s cancer, effective therapy may save your life.

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    OverviewSymptoms and CausesDiagnosis and TestsManagement and TreatmentPreventionOutlook / PrognosisLiving With

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    What causes liver lesions?

    Researchers aren’t sure why some lesions develop. Possible causes include: Scarring (cirrhosis) from chronic liver disease, which occurs with hepatitis B, hepatitis C and heavy drinking. Smoking. Hormones found in birth control pills.

    What are the symptoms?

    The symptoms you experience depend on the type of liver lesion. Benign lesions typically do not cause symptoms, especially when they are small. On rare occasions, they can become large enough to press on nearby organs. When this happens, you may experience abdominal pain. Liver cancer does not cause symptoms in its early stages. As the lesion grows, you may experience: Abdominal pain. Fatigue. Feeling full after eating small amounts of food. Loss of appetite. Lump you can feel toward the top right side of your stomach. Yellowing of the skin or whites of your eyes from jaundice. Advertisement

    How are liver lesions diagnosed?

    There is no single test that can diagnose all liver lesions. Your doctor may order a combination of tests to diagnose your liver lesions. The most important tests used are: Abdominal imaging such as ultrasound, CT scan and MRI. Tumor markers. These are blood tests that can diagnose certain types of liver lesions. Biopsy. This a procedure that allows the provider to obtain a tiny piece of the liver or liver lesion to examine under the microscope.

    How are liver lesions treated?

    Treatments of liver lesions depends on: The nature of the lesions: Is it cancer or not cancer (benign)? The size of the lesions: How big is it? The condition of the liver: Is it healthy or diseased?

    How are benign liver lesions treated?

    If benign liver lesions are small and don’t cause symptoms, no treatment is needed. Your provider may monitor them by repeating imaging. If benign liver lesions are large and cause symptoms, they can be removed by surgery.

    How is liver cancer treated?

    Liver cancers always need treatment. There are several options. Your healthcare provider will help you decide which one is best for you. Treatments for liver cancer include: Ablation: Ablation destroys the liver lesion with heat or chemicals. This works best in small lesions. Removal of the tumor: Surgery to remove the tumor usually works best if the liver is healthy. Liver transplantation: The whole liver may need to be removed and replaced with another whole or part of a liver. This is usually done when the liver is diseased (cirrhosis). Chemotherapy: Chemotherapy may be placed directly in the tumor in a certain procedure or given by mouth. Care at Cleveland Clinic Liver Disease Treatment Find a Doctor and Specialists Make an Appointment

    How can I prevent liver lesions?

    It’s difficult to prevent benign liver lesions. But you can lower your liver cancer risk by: Living a healthy lifestyle, which includes eating a balanced diet and getting plenty of physical activity. Drinking alcohol in moderation because it damages liver cells and can lead to cirrhosis. Avoiding hepatitis, which you can do by getting vaccinated, hand washing and practicing safe sex.

    What is the outlook for people with benign liver lesions?

    The outlook is often good. Benign liver lesions rarely grow, and they do not spread. And most lesions don’t need treatment.

    What is the outlook for people with liver cancer?

    It varies based on the type of cancer and how long the cancer has been there. Hepatocellular carcinoma: People with hepatocellular carcinoma have an excellent outlook (prognosis) when the cancer is found and treated early. These cancers often can be cured. Metastatic cancer (cancer that spread from another part of your body to the liver): This condition is more difficult to treat, and there are fewer options. Treatment will not cure the cancer, but can slow its growth and improve symptoms.

    How do liver lesions affect my health?

    The impact depends on your diagnosis: Benign liver lesions typically do not cause symptoms, spread or interfere with liver functioning. It will not have much, if any, impact on your daily life. Liver cancer can make you feel sick and run down in later stages. It also gets worse over time and can spread to other areas. Cancer treatment can take months to complete. During this time, you might not be able to work or take care of yourself. A note from Cleveland Clinic Liver lesions are abnormal growths that have various causes. Many do not need treatment. You might not know you have them. If you are at risk or experiencing symptoms, talk to your healthcare provider. They may recommend specialized testing or monitoring to check for changes that require additional care. And if imaging studies show signs of a liver lesion, remember that it might not be serious. Only a small number of these growths are cancerous. Medically Reviewed Last reviewed by a Cleveland Clinic medical professional on 05/18/2021. Learn more about our editorial process.

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  3. Feb 19, 2013 · A consideration of the differences between a Janeway’s lesion and an Osler’s node in infectious endocarditis. Chest. 1976; 70:239–243. Crossref Medline Google Scholar; 2. Tan JS, Kerr A Biopsies of the Janeway lesion of infective endocarditis. J Cutan Pathol. 1979; 6:124–129. Crossref Medline Google Scholar; 3. Mandell , Douglas ...

  4. Dec 2, 2023 · There are different types of benign liver lesions characterized by the cells they develop from. The three most common include: Hemangioma of the liver: This is the most common type that originates in blood vessels of the liver. Around 5% of the general population have liver hemangiomas. Focal nodular hyperplasia (FNH): This is the second most ...

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  5. Janeway lesion. Painless red flat papules on palms and soles. Janeway lesions are rare, non- tender, small erythematous or haemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes. [1] [2]

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