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  2. What causes pregnancy-induced hypertension (PIH)? The cause of PIH is unknown. Some conditions may increase the risk of developing PIH, including the following: pre-existing hypertension (high blood pressure) kidney disease. diabetes. PIH with a previous pregnancy. mother's age younger than 20 or older than 40. multiple fetuses (twins, triplets)

  3. Dec 15, 2021 · Abstract. Hypertensive disorders of pregnancy (HDP) remain one of the major causes of pregnancy-related maternal and fetal morbidity and mortality worldwide. Affected women are also at increased risk for cardiovascular disease later in life, independently of traditional cardiovascular disease risks. Despite the immediate and long-term ...

  4. Apr 28, 2022 · Hypertensive disorders in pregnancy (HDPs) are common pregnancy complications and leading causes of pregnancy-related death in the United States. What is added by this report? During 2017–2019, HDP prevalence among delivery hospitalizations increased from 13.3% to 15.9%.

  5. Jun 20, 2022 · In 2018, the classification was standardized with those of other countries, and “hypertensive disorders of pregnancy (HDP)” were considered to be present if hypertension existed during pregnancy and up to 12 weeks after delivery [ 3 ]. High blood pressure before pregnancy (chronic hypertension) is now included in the definition of HDP.

    • 10.1038/s41440-022-00965-6
    • 2022
    • Hypertens Res. 2022; 45(8): 1298-1309.
  6. Jun 1, 2001 · Abstract. Pregnancy-induced hypertension (PIH) is estimated to affect 7% to 10% of all pregnancies in the United States. Despite being the leading cause of maternal death and a major contributor of maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of PIH have not yet been fully elucidated.

    • Joey P. Granger, Barbara T. Alexander, William A. Bennett, Raouf A. Khalil
    • 2001
  7. Inadequate blood flow through the placenta. An atypical immune system response to the placenta. Dysfunction of the endothelial cells that line blood vessels. Pregnancy-induced hypertension is common in first pregnancies, possibly due to the body’s response to the placenta during its initial exposure.

  8. May 23, 2012 · Hypertension in pregnancy is a major cause of maternal morbidity and mortality in the United States. There is approximately one maternal death due to preeclampsia-eclampsia per 100,000 live births, with a case-fatality rate of 6.4 deaths per 10,000 cases [ 79, 80 ].

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