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  1. The smallpox vaccine is the first vaccine to be developed against a contagious disease. In 1796, the British doctor Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the 20th century.

  2. Jay Scott Greenspan (born September 23, 1959), known professionally as Jason Alexander, is an American actor, comedian, film director, and television presenter.. An Emmy and Tony winner, he is best known for his role as George Costanza in the television series Seinfeld (1989–1998), for which he was nominated for seven consecutive Primetime Emmy Awards and four Golden Globe Awards.

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