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  1. There is no cure for genital herpes. However, daily use of antiviral medicines can prevent or shorten outbreaks. Antiviral medicines also can reduce the chance of spreading it to others. Though several clinical trials have tested vaccines against genital herpes, there is no vaccine currently available to prevent infection.

  2. HSV-2 meningitis is a rare complication of HSV-2 genital herpes infection that affects women more than men ( 480 ). IV therapy should be considered until clinical improvement followed by oral antiviral therapy to complete >10 days of total therapy. Longer duration is recommended for CNS complications.

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  4. Herpes sores usually appear as one or more blisters on or around the genitals, rectum or mouth. This is known as having an “outbreak”. The blisters break and leave painful sores that may take a week or more to heal. Flu-like symptoms (e.g., fever, body aches, or swollen glands) also may occur during the first outbreak.

  5. Apr 24, 2024 · Division of Sexually Transmitted Disease Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC) Atlanta, Georgia, USA Corresponding Authors: K. Connolly, 5601 Fishers Lane, Rockville, MD 20852 ( kristie.connolly@nih.gov ), L. Bachmann, 1600 Clifton Road NE ...

  6. These systematic reviews were focused on four principal outcomes of STI therapy for each disease or infection: 1) treatment of infection on the basis of microbiologic eradication; 2) alleviation of signs and symptoms; 3) prevention of sequelae; and 4) prevention of transmission, including advantages (e.g., cost-effectiveness, single-dose ...

    • Kimberly A Workowski, Laura H Bachmann, Philip A Chan, Christine M Johnston, Christina A Muzny, Ina ...
    • 2021
  7. Apr 11, 2024 · Herpes, caused by herpes simplex virus (HSV), has two subtypes—HSV-1 and HSV-2. HSV can be transmitted through sexual contact. In severe cases HSV may lead to life-threatening or long-term complications, typically in the central nervous system. HSV is a leading cause of viral encephalitis—brain inflammation from a viral infection—and infectious blindness worldwide. Neonatal herpes, if ...

  8. Editorial. Sexually Transmitted Infections Treatment Guidelines, 2021. US Centers for Disease Control and Prevention (CDC) July 23, 2021. June 5, 2015. Persons who have or are at risk for sexually transmitted infections (STIs) Neisseria gonorrhoeae should now be treated with high-dose ceftriaxone (500 mg intramuscularly for persons <150 kg or 1 ...

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