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  1. www.ncbi.nlm.nih.gov › pmc › articlesGeneral Pathways of Pain Sensation and the Major...

    Jul 24, 2018 · The pathway that goes upward carrying sensory information from the body via the spinal cord towards the brain is defined as the ascending pathway, whereas the nerves that goes downward from the brain to the reflex organs via the spinal cord is known as the descending pathway. Pain is a vast subject and affects so many regions of an individual ...

  2. academic.oup.com › painmedicine › articlePain Pathways and Nervous System Plasticity: Learning and ...

    Mar 13, 2019 · Pain Pathways and Mechanisms: From Nociception to Central Processing. Pain pathways represent a complex sensory system, with cognitive, emotional, and behavioral elements having evolved to detect and integrate a protective response to noxious stimuli . In humans, this system involves both primitive spinal reflexes and complex conscious and ...

    • Bill McCarberg, John Peppin
    • 2019

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  4. www.nature.com › articles › nmCentral mechanisms of pathological pain | Nature Medicine

    Oct 14, 2010 · Abstract. Chronic pain is a major challenge to clinical practice and basic science. The peripheral and central neural networks that mediate nociception show extensive plasticity in pathological ...

    • Rohini Kuner
    • rohini.kuner@pharma.uni-heidelberg.de
    • 2010

  5. academic.oup.com › edited-volume › 3428215 Central Nervous System Pain Pathways - Oxford Academic

    Jul 10, 2018 · The spinal dorsal horn can be divided into six parallel laminae based on neuronal size and packing density (Rexed, 1952), and this scheme has been used to define the regions targeted by different types of primary afferent (Figure 15.1), as well as to define specific populations of spinal cord neurons.

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  7. link.springer.com › chapter › 10Basic Science: Pain Mechanisms and Pathways | SpringerLink

    Feb 11, 2022 · Pain physiology: the neural networks activated by painful stimuli and responsible for reaction to pain. It is composed of (1) peripheral sensory neurons that sense the stimuli ( nociceptors ); (2) pathways that transmit the stimuli from peripheral to central nervous system ( pain transmission pathways ); (3) sets of neurons that elicit ...

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