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Development of monoclonal antibodies
- César Milstein (born October 8, 1927, Bahía Blanca, Argentina—died March 24, 2002, Cambridge, England) was an Argentine-British immunologist who in 1984, with Georges Köhler and Niels K. Jerne, received the Nobel Prize for Physiology or Medicine for his work in the development of monoclonal antibodies.
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Mar 27, 2024 · César Milstein was an Argentine-British immunologist who in 1984, with Georges Köhler and Niels K. Jerne, received the Nobel Prize for Physiology or Medicine for his work in the development of monoclonal antibodies. Milstein attended the Universities of Buenos Aires (Ph.D., 1957) and Cambridge.
- The Editors of Encyclopaedia Britannica
César Milstein, CH, FRS (8 October 1927 – 24 March 2002) was an Argentine biochemist in the field of antibody research. Milstein shared the Nobel Prize in Physiology or Medicine in 1984 with Niels Kaj Jerne and Georges J. F. Köhler for developing the hybridoma technique for the production of monoclonal antibodies.
- 8 October 1927, Bahía Blanca, Argentina
- Biochemistry
César Milstein was awarded the 1984 Nobel Prize in Physiology or Medicine jointly with his former postdoctoral fellow Georges J. F. Köhler (AAI '85) and theoretician Niels Jerne (AAI '73). Milstein and Köhler won the prize for developing the hybridoma method of producing monoclonal antibodies.
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Mar 24, 2002 · Achievements. Milstein was important in advancing the knowledge of antibodies, notably their structure, expression and diversity. In 1984 he was awarded a Nobel Prize for his development, with Georges Kohler, of monoclonal antibodies in 1975.
- Bahia Blanca, Argentina
Jun 1, 2002 · Published: 01 June 2002. César Milstein, the father of modern immunology. Timothy A. Springer. Nature Immunology 3 , 501–503 ( 2002) Cite this article. 579 Accesses. 10 Citations. 3...
The more detailed structure of antibodies was a key topic of the time and Milstein soon became a leading figure in the field. His first publication was on the structure of the di-sulphide bonds of an antibody ‘light’ chain.