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      • In 1967, Belgian cytologist Christian de Duve discovered peroxisomes. Duve and his co-workers identified several oxidases within peroxisomes that are found to produce H 2 O 2 and catalase that decompose H 2 O 2 into oxygen and water. Due to their role in peroxide metabolism, Duve named them ‘peroxisomes’.
  1. Aug 1, 1998 · Based on the wealth of biochemical evidence accumulated over five years of research, de Duve and his colleagues proposed in 1955, in a paper that is now a classic, the existence of a new subcellular particle, which they named the lysosome to emphasize the hydrolytic properties of its enzymes [4].

  2. He made serendipitous discoveries of two cell organelles, peroxisomes and lysosomes, for which he shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and George E. Palade ("for their discoveries concerning the structural and functional organization of the cell"). [3]

  3. Christian René de Duve was a Belgian cytologist and biochemist who discovered lysosomes (the digestive organelles of the cell) and peroxisomes (organelles that are the site of metabolic processes involving hydrogen peroxide).

    • The Editors of Encyclopaedia Britannica
  4. Aug 8, 2013 · Christian de Duve, whose laboratory in Louvain discovered lysosomes in 1955 and defined peroxisomes in 1965, died at his home in Nethen, Belgium at the age of 95, on May 4, 2013.

    • David D. Sabatini, Milton Adesnik
    • 10.1073/pnas.1312084110
    • 2013
    • 2013/08/08
  5. Sep 11, 2009 · Following their first discovery in mouse kidney through microscopy, peroxisomes underwent extensive studies by Christian de Duve and Pierre Baudhuin. These researchers used rat liver cells to provide biochemical evidence for the presence of hydrogen peroxide (H 2 O 2 )-producing and -degrading activities in these sub-cellular structures, which ...

    • Navneet Kaur, Sigrun Reumann, Jianping Hu
    • 10.1199/tab.0123
    • 2009
    • Arabidopsis Book. 2009; 7: e0123.
  6. Mar 1, 2014 · The appellation “peroxisomes” was introduced by the Christian de Duve in 1965 to stress their content in enzymes either producing (oxidases) or breaking down (catalase) hydrogen peroxide [2]. This biochemical individualization of peroxisomes as a new class of subcellular organelles was not so easy.

  7. Christian de Duve, whose laboratory in Louvain discovered lysosomes in 1955 and defined peroxisomes in 1965, died at his home in Nethen, Belgium at the age of 95, on May 4, 2013.

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