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  1. Chronic myeloid leukemia (CML) is also known as chronic myelogenous leukemia. It's a type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood. About 15% of leukemias in adults are CML. About Chronic Myeloid Leukemia. Causes, Risk Factors, and Prevention. Early Detection, Diagnosis, and Staging.

  2. Feb 14, 2023 · Chronic myeloid (myelogenous) leukemia (CML) is blood cancer that starts in the blood-forming myeloid cells or stem cells in your bone marrow. Healthcare providers treat CML with innovative therapies that have turned CML from being a potentially life-threatening illness into a chronic illness.

  3. Jun 16, 2023 · The goal of chronic myelogenous leukemia treatment is to eliminate the blood cells that contain the BCR-ABL gene. For most people, treatment begins with targeted therapy that may help achieve a long-term remission of the disease.

  4. Nov 17, 2023 · Chronic myelogenous leukemia is a disease in which the bone marrow makes too many white blood cells. Leukemia may affect red blood cells, white blood cells, and platelets. Signs and symptoms of chronic myelogenous leukemia include weight loss and tiredness. Most people with CML have a gene mutation (change) called the Philadelphia chromosome.

  5. Chronic myeloid leukemia (CML) Is a cancer of the bone marrow and blood. CML is usually diagnosed in its chronic phase when treatment is very effective for most patients. CML has three phases. Click here to access CML statistics. What You Should Know.

  6. CML ensues when an abnormal pluripotent hematopoietic progenitor cell initiates excessive production of all myeloid lineage cells, primarily in the bone marrow but also in extramedullary sites (eg, spleen, liver).

  7. The most common sign of CML is an abnormal white blood cell count. (Blood counts are discussed further in Tests for Chronic Myeloid Leukemia.

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