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  1. Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.

  2. Feb 21, 2024 · What is congenital rubella syndrome? Congenital rubella syndrome (CRS) happens when a pregnant person becomes infected with rubella (German measles) and passes it on to the fetus. “Congenital” means “present at birth.” CRS causes a variety of issues during fetal development.

  3. Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.

  4. Congenital rubella syndrome (CRS) is an illness in infants that results from maternal infection with rubella virus during pregnancy. When rubella infection occurs during early pregnancy, serious consequences–such as miscarriages, stillbirths, and a constellation of severe birth defects in infants–can result.

  5. May 11, 2022 · However, if you're pregnant when you get rubella, the effect on your unborn child may be severe, and in some cases, fatal. Up to 90% of infants born to mothers who had rubella during the first 12 weeks of pregnancy develop congenital rubella syndrome. This syndrome can cause one or more problems, including: Growth delays; Cataracts; Deafness

  6. Aug 8, 2023 · However, maternal infection during the first trimester of pregnancy can cause a fetal malformation syndrome called congenital rubella syndrome. Rubella, also known as German Measles, is a viral illness characterized by maculopapular rash, lymphadenopathy, and fever.

  7. May 15, 2024 · Rubella is a leading cause of vaccine-preventable birth defects. When a woman is infected with the rubella virus during pregnancy, particularly in the first trimester, the newborn can have birth defects, known as congenital rubella syndrome (CRS).

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