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  1. Feb 13, 2024 · INTRODUCTION. Sepsis is a clinical syndrome characterized by a dysregulated host response to infection. There is a continuum of severity ranging from sepsis to septic shock. Although wide-ranging and dependent upon the population studied, mortality has been estimated to be ≥10 percent and ≥40 percent when shock is present [ 1,2 ].

  2. Feb 10, 2023 · Urine. Liquid from the wound. Mucus and saliva from the respiratory tract. Imaging tests. If the site of infection is not readily found, your health care provider may order more tests. Some examples of imaging tests are: X-ray. X-rays can show infections in your lungs. Ultrasound.

  3. diagnosis of sepsis, clinicians must obtain historical, clini-cal, laboratory, and radiographic data supportive of infec-tion and organ dysfunction. Table 1 summarizes...

  4. Under the new definition, sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, where organ dysfunction is defined as an increase in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score of 2 points or more, which is associated with an in-hospital mortality greater than 10%. 1.

  5. Key Points. Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. In septic shock, there is critical reduction in tissue perfusion and acute failure of multiple organs, including the lungs, kidneys, and liver, can occur.

  6. Sep 15, 2023 · INTRODUCTION. Sepsis is a clinical syndrome that has physiologic, biologic, and biochemical abnormalities caused by a dysregulated host response to infection. Sepsis and the inflammatory response that ensues can lead to multiple organ dysfunction syndrome and death.

  7. There is no single diagnostic test for sepsis, or one set of criteria that can identify sepsis with perfect accuracy, and thus it is important to note the following limitations of this surveillance definition, which has been optimized for