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1. id.wikipedia.org › wiki › Sitokrom_P450Sitokrom P450 - Wikipedia bahasa Indonesia, ensiklopedia bebas

   id.wikipedia.org › wiki › Sitokrom_P450

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   Sitokrom P450 (bahasa Inggris: Cytochrome P450, CYP) merupakan keluarga besar enzim berjenis hemeprotein yang berfungsi sebagai katalis oksidator pada lintasan metabolisme steroid, asam lemak, xenobiotik, termasuk obat, racun dan karsinogen.

2. en.wikipedia.org › wiki › Cytochrome_P450Cytochrome P450 - Wikipedia

   en.wikipedia.org › wiki › Cytochrome_P450

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   Cytochromes P450 ( P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. [1] . However, they are not omnipresent; for example, they have not been found in Escherichia coli. [2] .

   • Symbol: p450
   • Pfam: PF00067

   • InterPro: IPR001128
   • PROSITE: PDOC00081

3. People also ask

   What are cytochrome P450 enzymes?

   • Cytochrome P450 enzymes also function to metabolize potentially toxic compounds, including drugs and products of endogenous metabolism such as bilirubin, principally in the liver . The Human Genome Project has identified 57 human genes coding for the various cytochrome P450 enzymes.

   Cytochrome P450 - Wikipedia

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   What does cytochrome P450 stand for?

   • Cytochrome P450 stands for a superfamily of more than 50 closely related heme-containing enzymes, which can be divided into families (with at least 40% sequence homology on the amino acid level) and subfamilies (with at least 55% sequence homology), each with their own substrate specificity.

   Cytochrome P450 | SpringerLink

   link.springer.com/referenceworkentry/10.1007/978-3-642-16483-5_1460

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   What is the role of cytochrome P450 in drug therapy?

   • Last Update: April 24, 2023. Response to drugs varies considerably from person to person, and their clinical outcomes, ranging from treatment failure to adverse drug reactions, can be largely attributed to drug metabolism. The role of cytochrome P450 (CYP) has been vastly studied for years regarding its influence in drug therapy.

   Biochemistry, Cytochrome P450 - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK557698/

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   What cytochromes P450 is a monooxygenase reaction?

   • Notable ones include thromboxane synthase (CYP5), prostacyclin synthase (CYP8), and CYP74A ( allene oxide synthase ). The most common reaction catalyzed by cytochromes P450 is a monooxygenase reaction, e.g., insertion of one atom of oxygen into the aliphatic position of an organic substrate (RH), while the other oxygen atom is reduced to water:

   Cytochrome P450 - Wikipedia

   en.wikipedia.org/wiki/Cytochrome_P450

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4. en.wikipedia.org › wiki › CYP2D6CYP2D6 - Wikipedia

   en.wikipedia.org › wiki › CYP2D6

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   Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene. CYP2D6 is primarily expressed in the liver. It is also highly expressed in areas of the central nervous system, including the substantia nigra.

   • Aliases: CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1, cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 2D6

5. id.wikipedia.org › wiki › Sitokrom_P450_2D6Sitokrom P450 2D6 - Wikipedia bahasa Indonesia, ensiklopedia ...

   id.wikipedia.org › wiki › Sitokrom_P450_2D6

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   Sitokrom P450 2D6 (bahasa Inggris: cytochrome P450 2D6, CPD6, CYP2D, CYP2DL1, CYPIID6, P450C2D, P450DB1, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, P450-DB1, MGC120389, MGC120390, CYP2D6, EC 1.14.14.1) merupakan enzim mono oksigenase dari keluarga sitokrom P450 yang berfungsi sebagai katalisator berbagai reaksi kimiawi organik pada metabolisme ...

6. www.ncbi.nlm.nih.gov › books › NBK557698Biochemistry, Cytochrome P450 - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK557698

   Apr 24, 2023 · Cytochrome p450 is a superfamily of membrane-bound hemoprotein isozymes with distinct classifications. While present in most body tissues, CYP enzymes predominantly occupy the liver, intestines, and kidneys, with their highest concentration in the liver.

7. link.springer.com › referenceworkentry › 10Cytochrome P450 | SpringerLink

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   Jan 1, 2017 · CYP450. Definition. Cytochrome P450 stands for a superfamily of closely related proteins that protect the individual against potentially harmful substances by modifying these substances by oxidation, hydroxylation, dealkylation, or dehalogenation, thereby increasing polarity and solubility and thus facilitating excretion from the body.