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   In·trin·sic fac·tor

   /inˈtrinzik/

   noun

   • 1. a substance secreted by the stomach which enables the body to absorb vitamin B12. It is a glycoprotein.

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2. People also ask

   Where is intrinsic factor produced?

   • Intrinsic factor is produced by specialized mucosa cells called oxyntic cells located in the stomach lining. It is essential for the uptake of vitamin B 12 at the end of the small intestine. This glycoprotein has two binding sites: one for binding B 12 and one for a cell receptor that attaches to the bound intrinsic factor and B 12.

   Intrinsic Factor - The Definitive Guide | Biology Dictionary

   biologydictionary.net/intrinsic-factor/

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   What is intrinsic factor & how does it work?

   • Intrinsic factor is a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining. Intrinsic factor binds to vitamin B12. After attaching, intrinsic factor and B12 travel to the intestines to be absorbed into the bloodstream. Vitamin B12 is needed for red blood cells to form and grow.

   Intrinsic factor: MedlinePlus Medical Encyclopedia

   medlineplus.gov/ency/article/002381.htm

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   What is intrinsic factor & extrinsic factor?

   • The term intrinsic factor was coined in the late 1920s by the American physician William B. Castle, whose research into the cause of pernicious anemia indicated that two substances were involved: one that is produced in the body (intrinsic) and the other—an extrinsic factor, later identified as vitamin B 12 —that is supplied in the diet.

   Intrinsic factor | Vitamin B12, Gastric Juices & Stomach Cells

   www.britannica.com/science/intrinsic-factor

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   What is intrinsic factor deficiency?

   • Intrinsic factor deficiency or the presence of intrinsic factor antibody, however, causes symptoms such as anemia at a very early stage. We need vitamin B for various physiological processes. The main intrinsic factor function is its role in red blood cell maturation. Other roles are DNA synthesis and nerve cell maintenance.

   Intrinsic Factor - The Definitive Guide | Biology Dictionary

   biologydictionary.net/intrinsic-factor/

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3. en.wikipedia.org › wiki › Intrinsic_factorIntrinsic factor - Wikipedia

   en.wikipedia.org › wiki › Intrinsic_factor

   • Cached

   Intrinsic factor (IF), cobalamin binding intrinsic factor, also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B 12 later on in the distal ileum of the small intestine.

   • Aliases: CBLIF, IF, IFMH, INF, TCN3, gastric intrinsic factor, intrinsic factor, Intrinsic factor , IF, cobalamin binding intrinsic factor, GIF

4. biologydictionary.net › intrinsic-factorIntrinsic Factor - The Definitive Guide | Biology Dictionary

   biologydictionary.net › intrinsic-factor

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   Nov 12, 2020 · Intrinsic factor (IF) is a glycoprotein secreted into the gastric juice. It has three synonyms: It is composed of carbohydrate (glyco) and protein. One molecule of intrinsic factor binds to one molecule of vitamin B. Another name for this vitamin is cobalamin (Cbl).

5. www.merriam-webster.com › dictionary › intrinsic factorIntrinsic factor Definition & Meaning - Merriam-Webster

   www.merriam-webster.com › dictionary › intrinsic factor

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   The meaning of INTRINSIC FACTOR is a substance produced by normal gastrointestinal mucosa that facilitates absorption of vitamin B12.

6. medlineplus.gov › ency › articleIntrinsic factor: MedlinePlus Medical Encyclopedia

   medlineplus.gov › ency › article

   • Cached

   Jan 25, 2022 · Medical Encyclopedia →. Intrinsic factor is a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining. Information. Intrinsic factor binds to vitamin B12. After attaching, intrinsic factor and B12 travel to the intestines to be absorbed into the bloodstream.

7. www.britannica.com › science › intrinsic-factorIntrinsic factor | Vitamin B12, Gastric Juices & Stomach Cells

   www.britannica.com › science › intrinsic-factor

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   intrinsic factor, a glycoprotein ( i.e., a complex compound containing both polysaccharide and protein components) with which vitamin B 12 ( cyanocobalamin) must combine to be absorbed by the gut. Intrinsic factor is secreted by parietal cells of the gastric glands in the stomach, where it binds with the vitamin.

   • Author: The Editors of Encyclopaedia Britannica

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9. www.ncbi.nlm.nih.gov › books › NBK546655Physiology, Gastric Intrinsic Factor - StatPearls - NCBI ...

   www.ncbi.nlm.nih.gov › books › NBK546655

   Jul 17, 2023 · The intrinsic factor (IF) is a glycoprotein produced by the parietal cells (oxyntic cells) located at the gastric body and fundus. Intrinsic factor plays a crucial role in the transportation and absorption of the vital micronutrient vitamin B12 (cobalamin, Cbl) by the terminal ileum.

10. www.mountsinai.org › intrinsic-factorIntrinsic factor Information | Mount Sinai - New York

    www.mountsinai.org › intrinsic-factor

    • Cached

    Health Library. Intrinsic factor is a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining. Information. Intrinsic factor binds to vitamin B12. After attaching, intrinsic factor and B12 travel to the intestines to be absorbed into the bloodstream.