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2. Organization and Functions of the Sebaceous Gland. In its mature form, SGs are acinar holocrine-secreting appendages of the epidermis (Figure 1).As crucial component of the pilosebaceous unit, the SG is connected to the junctional zone (JZ) of the HF, an area that is localized to the upper permanent part of the HF.
Sebaceous carcinoma is a rare and aggressive type of skin cancer that develops in a sebaceous gland, which produces sebum, a mixture of complex oils that help to lubricate the skin. Sebaceous carcinoma is also known as sebaceous gland carcinoma, sebaceous gland adenocarcinoma or meibomian gland carcinoma. Most areas of the skin contain these sebaceous glands — they are largest and most ...
Jan 19, 2021 · Abstract. Sebaceous carcinoma is an aggressive skin cancer with a 5-year overall survival rate of 78% for localized/regional disease and 50% for metastatic disease. The incidence of this cancer has been increasing in the United States for several decades, but the underlying reasons for this increase are unclear. In this article, we review the epidemiology and genetics of sebaceous carcinoma ...
Mar 13, 2019 · Sebaceous adenoma is the most common sebaceous lesion associated with this syndrome. Lesions that develop in patients with MTS more commonly occur on the trunk and extremities. Other cutaneous lesions seen in MTS include sebaceous epithelioma, sebaceous carcinoma and keratoacanthoma, the latter often with sebaceous features.
Mar 26, 2022 · To assess the prognostic value of T category of the 8th edition of American Joint Committee on Cancer (AJCC) classification in periocular sebaceous gland carcinoma (SGC). Retrospective ...
Apr 8, 2021 · Sebaceous gland carcinoma usually presents as a small firm nodule resembling chalazion, and majority of the premalignant and malignant lesions misdiagnosed as chalazion are primary cases. Hence, the need of histopathological examination in every such case cannot be undermined.
Oct 14, 2014 · B-lymphocyte-induced nuclear maturation protein 1 (BLIMP1) was previously reported to define a sebaceous gland (SG) progenitor population in the epidermis. However, the recent identification of multiple stem cell populations in the hair follicle junctional zone has led us to re-evaluate its function …
