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      • Neonatal sepsis is invasive infection, usually bacterial, occurring during the neonatal period. Signs are multiple, nonspecific, and include diminished spontaneous activity, less vigorous sucking, apnea, bradycardia, temperature instability, respiratory distress, vomiting, diarrhea, abdominal distention, jitteriness, seizures, and jaundice.
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  2. May 09, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1].

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
  3. The pediatric consensus definition for sepsis, established in 2005 to support the trial of activated protein C for the treatment of pediatric sepsis, was intended for all children (<18 years old) and including term (≥37 weeks completed gestation) neonates . Preterm neonates (<37 weeks completed gestation) were specifically excluded from the pediatric consensus definitions and neonatal-perinatal subspecialists were not represented among the international pediatric consensus experts.

    • James L. Wynn
    • 2016
  4. Jul 24, 2016 · Sepsis neonatorum refers to a constellation of clinical and laboratory findings associated with invasive infection during the first 30 days of life. Traditionally, the neonatal sepsis syndrome has been associated with bacteremia, but it may be caused by a variety of pathogens, including bacteria, viruses, and fungi.

  5. Neonatal sepsis is any infection involving an infant during the first 28 days of life. Neonatal sepsis is also known as "sepsis neonatorum." The infection may involve the infant globally or may be limited to just one organ (such as the lungs with pneumonia). It may be acquired prior to birth (intrauterine sepsis) or after birth (extrauterine sepsis).

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