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  1. May 9, 2023 · Summary. Early diagnosis and timely intervention with antibiotics, fluid resuscitation, and vasoactive medications are the most important interventions in sepsis. The implementation of protocols, resource-adjusted sepsis bundles, and advanced technologies will have an impact on reducing sepsis mortality. Keywords: Antibiotic management, Fluid ...

  2. Jan 22, 2024 · The importance of defining pediatric sepsis. In 2016, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as life-threatening organ dysfunction ...

  3. Feb 10, 2023 · Symptoms of sepsis. Symptoms of sepsis may include: Change in mental status. Fast, shallow breathing. Sweating for no clear reason. Feeling lightheaded. Shivering. Symptoms specific to the type of infection, such as painful urination from a urinary tract infection or worsening cough from pneumonia. Symptoms of sepsis are not specific.

  4. Jan 1, 2015 · The case definition for confirmed neonatal tetanus is “a neonate with the normal ability to suck and cry during the first two days of life, and between 3 and 28 days of age cannot suck normally and becomes stiff or has spasms (ie, jerking of the muscles)”. 8 In 1988, the World Health Assembly passed a resolution to eliminate neonatal ...

  5. Mar 19, 2020 · Overview of neonatal sepsis and definitions. Sepsis represents a major contributor to global mortality and has been declared as a priority by the WHO. 1 The highest sepsis incidence across all age ...

  6. Nov 2, 2020 · The area under the curve (AUC) for pediatric SOFA score was 93.9% (95%CI 89.7 to 98.0%). Conclusion Pediatric SOFA score >= 8 is the optimal cut-off for predicting life-threatening organ dysfunction in pediatric sepsis. Multicenter revalidation is needed to find the most optimal cut-off point for general use in Indonesia.

  7. Neonatal sepsis can be early onset (≤ 3 days of birth) or late onset (after 3 days). Early-onset sepsis usually results from organisms acquired intrapartum, and symptoms appear within 6 hours of birth. Late-onset sepsis is usually acquired from the environment and is more likely in preterm infants, particularly those with prolonged ...

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