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  1. Specifically, the Third International Consensus Definitions for Sepsis and Septic Shock (Balamuth 2022) stresses that sepsis is a function of 4 variables, namely: threat to life. organ dysfunction (using pSOFA score) dysregulated host response. presence of highly suspected or documented infection.

  2. Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatric Research (2020) 88:2–4; https://doi.org/10.1038/s41390-020-0850-5. OVERVIEW OF NEONATAL SEPSIS...

    • Eleanor J. Molloy, James L. Wynn, Joseph Bliss, Joyce M. Koenig, Fleur M. Keij, Matt McGovern, Helmu...
    • 2020
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  4. Sep 29, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1].

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  5. Mar 19, 2020 · The criteria to define infection and sepsis are essential in the neonatal population to limit overdiagnosis, but they are not part of the adult Sepsis-3 definitions.

    • Eleanor J. Molloy, James L. Wynn, Joseph Bliss, Joyce M. Koenig, Fleur M. Keij, Matt McGovern, Helmu...
    • 2020
  6. May 9, 2023 · Pediatric definitions remain despite the new 2016 adult definitions and criteria (Sepsis-3), where “sepsis” is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and “septic shock” is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of ...

  7. Jul 6, 2016 · Definition of Sepsis. Adult and pediatric intensivists currently use generally accepted definitions for sepsis for goal-based therapeutic interventions.6, 7, 8, 9 These definitions are critical to facilitate epidemiologic studies, to accurately determine disease prevalence, to select patients for clinical trials, and ultimately to improve the ...

  8. Oct 1, 2020 · What is neonatal sepsis? Neonatal sepsis, or illness caused by systemic bacterial infection, is a major cause of paediatric morbidity and mortality. The 2015 Global Burden of Disease study identified neonatal sepsis as the third most common cause of newborn …

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