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  1. What is sepsis in newborns? Sepsis is a serious medical condition caused by the body's response to an infection. A newborn who has an infection and develops sepsis can have inflammation (swelling) throughout the body, leading to organ failure. Cleveland Clinic is a non-profit academic medical center.

  2. Neonatal sepsis is a common, devastating, and expensive disease with life-long impact plagued by a lack of accurate diagnostic and prognostic testing. Management options and outcomes have not changed for the last 30 years. There is remarkable heterogeneity among studies regarding the case definition of neonatal sepsis.

    • James L. Wynn
    • 2016
  3. May 09, 2022 · Neonatal sepsis refers to an infection involving bloodstream in newborn infants less than 28 days old. It continues to remain a leading cause of morbidity and mortality among infants, especially in middle and lower-income countries.

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  5. Medical Editor: William C. Shiel Jr., MD, FACP, FACR Neonatal sepsis is any infection involving an infant during the first 28 days of life. Neonatal sepsis is also known as "sepsis neonatorum." The infection may involve the infant globally or may be limited to just one organ (such as the lungs with pneumonia ).

  6. Neonatal sepsis is invasive infection, usually bacterial, occurring during the neonatal period. Signs are multiple, nonspecific, and include diminished spontaneous activity, less vigorous sucking, apnea, bradycardia, temperature instability, respiratory distress, vomiting, diarrhea, abdominal distention, jitteriness, seizures, and jaundice.

  7. Sepsis is the body’s extreme response to an infection. It is a life-threatening medical emergency. Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Infections that lead to sepsis most often start in the lung, urinary tract, skin, or gastrointestinal tract. Without timely treatment, sepsis can ...

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