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Jan 19, 2022 · A vaccine can help prevent dengue, which is caused by four distinct, but closely related dengue viruses, DENV-1, DENV-2, DENV-3, and DENV-4. Only one dengue vaccine is currently available for use: A tetravalent, live-attenuated dengue vaccine (Dengvaxia®)
Feb 2, 2024 · Stephanie Soucheray, MA. Dengue. Sesai/ Flickr cc. Results of a phase 3 trial in the New England Journal of Medicine ( NEJM) show 80% protection for the single-dose tetravalent (four-strain) Butantan-Dengue Vaccine (Butantan D-V) among participants with no evidence of previous dengue exposure and 89% protection in those with a history of exposure.
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Apr 20, 2018 · A safe, effective and affordable dengue vaccine against the four strains would represent a major advance for the control of the disease and could be an important tool for reaching the WHO goal of reducing dengue morbidity by at least 25% and mortality by at least 50% by 2020.
May 01, 2019. Español. The U.S. Food and Drug Administration announced today the approval of Dengvaxia, the first vaccine approved for the prevention of dengue disease caused by all dengue...
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May 24, 2022 · A new and important concern is how individuals will react to dengue vaccines, which arises in regions affected by the Zika virus (ZIKV). ADE has also been reported in individuals infected by DENV-2 who were previously infected by ZIKV . Evidence in animal models show this event for both DENV and ZIKV when using live attenuated vaccines .
Apr 15, 2023 · Dengue is a major global public health problem requiring a safe and efficacious vaccine as the foundation of a comprehensive countermeasure strategy. Despite decades of attempts, the world has...
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Apr 23, 2024 · So far one vaccine (QDenga) has been approved and licensed in some countries. However, it is recommended only for the age group of 6 to 16 years in high transmission settings. Several additional vaccines are under evaluation. WHO response. WHO responds to dengue in the following ways:
