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Dengue Virus. Dengue virus is one of the most widespread mosquito-borne viruses worldwide, with an estimated annual infection rate around 390 million.143 Dengue fever is a self-limiting, nonspecific illness characterized by fever, headache, myalgia, and constitutional symptoms caused by the dengue virus (serotypes 1 to 4).
Feb 5, 2010 · Introduction. Dengue is caused by infection with any one of the four dengue virus (DENV) serotypes (DENV1-4), and it is the most prevalent arboviral disease worldwide. 1, 2 DENV infections cause illness in tens of millions each year throughout the tropics and subtropics, severe morbidity in approximately 2 million persons/year, and approximately 20,000 deaths/year. 3 The clinical ...
In recent years, dengue infection has been particularly prevalent in India, Southeast Asia, Brazil, and Guangdong Province, China. In this article, we present a brief summary of the biological characteristics of dengue virus and associated flaviviruses, and outline the progress on studies of vaccines and drugs based on potential targets of the ...
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes ...
Mar 5, 2019 · Introduction. Dengue virus (DENV), a Flavivirus genus member of the Flaviviridae family, is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. The virus is endemic in many tropical and subtropical countries where it is associated with outbreaks of dengue disease.
Mar 3, 2002 · The overall fit of the 90 TBEV E dimer structures to the cryoEM map of dengue virus gives a satisfying, close-packing arrangement ( Figures 3B and 3D ). The dengue virus structure ( Figure 3C) has sets of three, nearly parallel dimers. These sets associate to form a “herringbone” configuration on the viral surface.
Apr 13, 2023 · Dengue is defined by a combination of ≥2 clinical findings in a febrile person who traveled to or lives in a dengue-endemic area. Clinical findings include nausea, vomiting, rash, aches and pains, a positive tourniquet test, leukopenia, and the following warning signs: abdominal pain or tenderness, persistent vomiting, clinical fluid ...
