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  1. 2 days ago · Dengue, a significant mosquito-borne disease, presents a global health challenge with limited treatment options. Recently, there have been estimates of 390 million dengue infections annually worldwide. Thus, Dengue viruses (DENV) continue to result in a severe burden on human health all over the world. Here, we are introducing the Anti-Dengue Peptide Database (ADPDB) as a comprehensive ...

  2. 4 days ago · As dengue expands globally and many vaccines are under trials, there is a growing recognition of the need for assessing T cell immunity in addition to assessing the functions of neutralizing antibodies during these endeavors. While several dengue-specific experimentally validated T cell epitopes are known, less is understood about which of these epitopes are conserved among circulating dengue ...

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  4. 5 days ago · Dengue virus (DENV) is a continuing global threat that puts half of the world’s population at risk for infection. This mosquito-transmitted virus is endemic in over 100 countries. When a mosquito takes a bloodmeal, virus is deposited into the epidermal and dermal layers of human skin, infecting a variety of permissive cells, including keratinocytes, Langerhans cells, macrophages, dermal ...

  5. 5 days ago · Updated data as of epidemiological week 52 for Dengue, 52 for chikungunya and 52 for Zika of 2021. DENGUE. 1,269,271 cases. 127.94 cases x 100,000 Pop. 3,272 severe dengue (0.3%) 437 deaths. 0.034% case fatality rate (CFR) Saint Bartolome is he country with the highest cumulative incidence. CHIKUNGUNYA.

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  6. 4 days ago · Dengue, a mosquito-borne viral disease caused by any of the four dengue virus sero- types (DENV1–4), is an emerging global epidemic, with an estimated 390 million annual infections and 100 million cases of clinical disease [1].

  7. 6 days ago · plaque assay on Huh7.5.1 cells. West Nile Virus (Kunjin strain CH 16532) was a gift from Dr. J. F. Anderson. The yellow fever virus was generated by culturing the yellow fever YF-VAX 17D-204 vaccine in HAP1 cells. Chikungunya virus (CHIKV 181/25) was a gift from Dr. Margaret Kielian. All virus infection assays were conducted following the BSL2

  8. 4 days ago · Arboviral situation summary. In the Region of the Americas, between epidemiological week (EW) 1 and EW 53 of 2020, a total of 2,457,864 cases of arboviral disease were reported. Of these, 2,331,840 ( 94.9 % ) were dengue cases, 103,046 ( 4.2 % ) chikungunya cases, and 22,978 ( 0.9 % ) were Zika cases. Country specific data on case counts and ...

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