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Oct 5, 2022 · Dengue is a febrile illness caused by infection with one of four dengue viruses (DENV) transmitted by Aedes aegypti or Aedes albopictus mosquitoes during the taking of a blood meal [ 1-3 ]. Infection may be asymptomatic or present with a broad range of clinical manifestations including a mild febrile illness to a life-threatening shock syndrome.
Sep 7, 2020 · Infection is caused by any one of four closely related dengue viruses (called serotypes) and these can lead to a wide spectrum of symptoms, including some which are extremely mild (unnoticeable) to those that may require medical intervention and hospitalization. In severe cases, fatalities can occur.
Oct 24, 2019 · 24 October 2019 | Q&A. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. The incidence of dengue has increased 30-fold over the last 50 years.
Apr 25, 2024 · Participants who had tetravalent dengue purified inactivated vaccine prime and live-attenuated vaccine boost were unprotected against dengue virus-1 infection and further showed increased clinical, immunological, and transcriptomic evidence for inflammation potentially mediated by pre-existing infection-enhancing antibodies. This study highlights the impact of small cohort, human challenge ...
Aug 14, 2023 · INTRODUCTION — Substantial gaps remain in the comprehensive understanding of the pathogenesis of dengue virus (DENV) infections. In large part, this limitation is related to the lack of a suitable animal model of disease . Rhesus monkeys develop RNAemia and viremia similar in a pattern to humans after DENV challenge but do not develop ...
Aug 18, 2016 · Introduction. Dengue is currently one of the world's most important neglected tropical diseases 1 and its incidence has increased >30-fold in recent decades alongside the geographical expansion...
Jul 11, 2023 · Dengue is a febrile illness caused by a flavivirus transmitted by Aedes aegypti or Aedes albopictus mosquitoes while taking a blood meal. There are four dengue virus (DENV) types (DENV-1, DENV-2, DENV-3, and DENV-4), all of which are capable of inducing severe disease (dengue hemorrhagic fever [DHF]/dengue shock syndrome [DSS]).
