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  1. Natural vertical transmission of dengue virus in Aedes ...

    parasitesandvectors.biomedcentral.com/articles/...

    Dengue is of great concern in various parts of the world, especially in tropical and subtropical countries where the mosquito vectors Aedes aegypti and Aedes albopictus are present. The transmission of this virus to humans, by what is known as horizontal transmission, occurs through the bite of infected females of one or other of the two mosquito species. Furthermore, an infected female or ...

  2. Dengue Virus Entry as Target for Antiviral Therapy

    www.hindawi.com/journals/jtm/2012/628475

    Dengue virus (DENV) infections are expanding worldwide and, because of the lack of a vaccine, the search for antiviral products is imperative. Four serotypes of DENV are described and they all cause a similar disease outcome. It would be interesting to develop an antiviral product that can interact with all four serotypes, prevent host cell infection and subsequent immune activation. DENV ...

  3. Mechanism of dengue virus entry into cells | EurekAlert ...

    www.eurekalert.org/pub_releases/2014-02/aiop-mod...

    Mechanism of dengue virus entry into cells Discovery by North Carolina researchers described at biophysical society meeting may advance development of vaccines to fight global, mosquito-borne scourge

  4. Reaction Mechanism of the Dengue Virus Serine Protease: A QM ...

    www.researchgate.net/publication/303908061...

    Request PDF | Reaction Mechanism of the Dengue Virus Serine Protease: A QM/MM study | The dengue virus (DENV) is the causative agent of the viral infection dengue fever. In spite of all the ...

  5. Mar 21, 2016 · 14-3-3ɛ serves a crucial function in antiviral immunity by mediating the translocation of RIG-I from the cytosol to mitochondria. Chan and Gack have found that the NS3 protein of Dengue virus ...

  6. The role of lipids in the inception, maintenance and ...

    www.nature.com/articles/s41598-018-30385-x

    Dengue virus (DENV) is an arbovirus transmitted by mosquitoes of the genus Aedes, such as Aedes aegypti and Aedes albopictus.DENV is associated with outbursts of febrile diseases in the tropics ...

  7. Mechanism of Enhanced Immature Dengue Virus Attachment to ...

    www.sciencedirect.com/science/article/pii/S...

    Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody Author links open overlay panel Melissa Wirawan 1 2 9 Guntur Fibriansah 1 2 9 Jan K. Marzinek 3 4 9 Xin Xiang Lim 4 Thiam-Seng Ng 1 2 Adelene Y.L. Sim 3 Qian Zhang 1 2 Victor A. Kostyuchenko 1 2 Jian Shi 2 4 Scott A. Smith 5 6 Chandra S. Verma 3 ...

  8. How Dengue Fever Spreads and Affects the Human Body ...

    getcured.xyz/how-dengue-fever-spreads-and...

    Dec 15, 2017 · How Dengue Virus Replicates inside the Body? Now you came to know that how dengue virus spreads and infects the body. Let’s have a little discussion on Virus Replication inside the body – Once inside the skin, dengue virus binds to Langerhans cells (a population of dendritic cells in the skin that identifies pathogens).

  9. How Dengue Virus Infects Cells | National Institutes of ...

    www.nih.gov/.../how-dengue-virus-infects-cells

    The virus that causes dengue is transmitted by mosquitoes. Dengue fever usually starts with a fever, joint pain, rash and nausea. Without treatment, the virus can cause damage to blood and lymph vessels and lead to dengue hemorrhagic fever, which is marked by difficulty breathing, bruising and bleeding from the nose, gums or under the skin.

  10. Antiviral Research and Development Against Dengue Virus

    www.who.int/tdr/research/ntd/dengue/dengue_full...

    The introduction of dengue as a druggable disease 11 Diagnostics, and what does it tells us for antiviral therapy ? 11 Current treatment 11 Part 2. Dengue 13 Preamble 13 The Dengue Virus 13 The DENV targets for antiviral research 13 Overview of genome organisation 14 Overview of the DV particle and DV proteins as targets for drugs 14