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    • Dengue virus mechanism

      • When a mosquito carrying dengue virus bites a person, the virus enters the skin together with the mosquito's saliva. It binds to and enters white blood cells, and reproduces inside the cells while they move throughout the body.
      en.wikipedia.org/wiki/dengue_fever#:~:text=When%20a%20mosquito%20carrying%20dengue%20virus%20bites%20a,the%20cells%20while%20they%20move%20throughout%20the%20body.
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  2. Dengue fever - Wikipedia

    en.wikipedia.org/wiki/Dengue_fever

    1 day ago · Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash.

  3. Antibody-dependent enhancement - Wikipedia

    en.wikipedia.org/wiki/Antibody-dependent_enhancement

    5 days ago · Infection with dengue virus induces the production of neutralizing homotypic immunoglobulin G (IgG) antibodies which provide lifelong immunity against the infecting serotype. Infection with dengue virus also produces some degree of cross-protective immunity against the other three serotypes.

  4. Flavivirus - Wikipedia

    en.wikipedia.org/wiki/Flavivirus

    Sep 13, 2020 · The 5'UTRs are 95–101 nucleotides long in Dengue virus. There are two conserved structural elements in the Flavivirus 5'UTR, a large stem loop (SLA) and a short stem loop (SLB). SLA folds into a Y-shaped structure with a side stem loop and a small top loop.

  5. Scientists Find Way to Reduce Inflammation from Vaccines ...

    www.labroots.com/trending/drug-discovery-and...

    Sep 13, 2020 · In mice with dengue, for example, they found that the molecule helped the body produce more antibodies to neutralize the virus. Meanwhile, in those with HIV, they found it also helped produce more antibodies that targeted hard-to-reach areas of the virus. It was also able to enhance a pre-existing flu vaccine's efficacy.

  6. Gaining insights on immune responses to the novel coronavirus ...

    www.sciencedirect.com/science/article/pii/S...

    5 days ago · Previously, ADE has been investigated massively in dengue virus [, , ], HIV and Ebola infections. Based on SARS-CoV in vitro studies and mouse models, ADE dysregulates the immune response provoking cytokine surge, lymphopenia and inflammation-based injuries [ 54 ] in lung or other parts of the body in severely infected individuals [ 60 , 61 ].

    • Mahsa Hajivalili, Maryam Hosseini, Maryam Hosseini, Mostafa Haji-Fatahaliha
    • 2020
    • The mechanism of the enhanced immature dengue virus infection by human prM antibody
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    • Science in Action: Deadly Dengue Virus | California Academy of Sciences
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    • Dengue Virus infection
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    • NS1 Protein Linked to Fatal Dengue Disease
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  7. Metal-organic frameworks for virus detection - sciencedirect.com

    www.sciencedirect.com/science/article/pii/S...

    6 days ago · Virus severely endangers human life and health, the detection of virus is essential for the prevention and treatment of associated disease. Metal-orga…

  8. Transcriptomic analysis of chicken immune response to ...

    www.sciencedirect.com/science/article/pii/S...

    6 days ago · Newcastle disease virus (NDV) is a contagious poultry paramyxovirus, leading to substantial economic losses to the poultry industry. Here, RNA-seq was…

  9. Zika virus - Wikipedia

    en.wikipedia.org/wiki/Zika_virus

    Sep 13, 2020 · Zika virus is related to the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Since the 1950s, it has been known to occur within a narrow equatorial belt from Africa to Asia. From 2007 to 2016 [update] , the virus spread eastward, across the Pacific Ocean to the Americas, leading to the 2015–2016 Zika virus epidemic .

  10. Antiviral drug - Wikipedia

    en.wikipedia.org/wiki/Antiviral_drug

    Sep 13, 2020 · One anti-viral strategy is to interfere with the ability of a virus to infiltrate a target cell. The virus must go through a sequence of steps to do this, beginning with binding to a specific "receptor" molecule on the surface of the host cell and ending with the virus "uncoating" inside the cell and releasing its contents. Viruses that have a lipid envelope must also fuse their envelope with the target cell, or with a vesicle that transports them into the cell before they can uncoat.

  11. Identification of novel human USP2 inhibitor and its putative ...

    www.sciencedirect.com/science/article/pii/S...

    Sep 13, 2020 · •Human ubiquitin carboxyl-terminal hydrolase-2 (USP2) inhibitors, such as thiopurine analogs, have been reported to inhibit SARS-CoV papain-like prote…