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How the Dengue Virus Tricks the Immune System. Figure 1: Dengue viral infection. (A) A person is infected with the dengue virus when an infected mosquito bites the person’s skin. (B) The dengue ...
Jan 24, 2019 · Dengue is a viral illness that is spread primarily by Aedes mosquitoes and infects ~390 million people each year worldwide 1.It is caused by dengue virus (DENV), which belongs to the family of ...
Sep 30, 2021 · Regulation of cell death via autophagy during Dengue virus infection: The entry of Dengue virus induces autophagy in the infected cell. The mechanisms of autophagy post-DENV infection are: A. Induction of ER stress to trigger the UPR responses, out of which 2 pathways, involving IRE1α and PERK, respectively, lead to the formation of ...
The dengue virus is a tiny structure that can only replicate inside a host organism. The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are found in the same regions of ...
Dengue virus. Dengue virus ( DENV) is the cause of dengue fever. It is a mosquito -borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...
Oct 31, 2019 · On the other hand, in the dengue virus, NS1 anchors the replication complex to the host endoplasmic reticulum membrane, and interacts directly with NS4B, As a result, it plays an important role in the viral replication process. Furthermore, YFV and DENV are associated with hemorrhagic fever, this may be due to the increased vascular permeability.