Deaths. ~40,000 (2017) Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Recovery generally takes two to seven days.
4 days ago · The 2017 dengue vaccine controversy in the Philippines involved a vaccination program run by the Philippines Department of Health (DOH). The DOH vaccinated schoolchildren with Sanofi Pasteur's CYD-TDV (Dengvaxia) dengue vaccine. Some of the children who received the vaccine had never been infected by the dengue virus before.
5 days ago · Dengue virus is transmitted by mosquitoes and threatens more than half of the world population. In the absence of an effective vaccine and therapeutics and with a declining efficacy of insecticide, there is an urgent need to develop novel interventions. Here, we deployed an approach that combines metabolomics with molecular biology in mosquitoes. We revealed that dengue virus reconfigures the ...
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3 days ago · Infection with dengue virus induces the production of neutralizing homotypic immunoglobulin G (IgG) antibodies which provide lifelong immunity against the infecting serotype. Infection with dengue virus also produces some degree of cross-protective immunity against the other three serotypes.
Oct 18, 2020 · New Mechanism for Identifying Drugs for Dengue Discovered New mechanism for designing antiviral drugs for dengue virus has been identified. The study details are published in Proceedings of the...
5 days ago · Chikungunya virus (CHIKV) is a significant human pathogen that causes debilitating and long-lasting arthritis. Currently, there is no approved vaccine or specific therapeutic. We show that two highly potent anti-CHIKV antibodies—CHK-124 and CHK-263—can inhibit multiple steps of the CHIKV infection cycle and determined their cryogenic electron microscopy structures in complex with CHIKV ...
Guillain–Barré syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. Typically both sides are involved and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body.
6 days ago · If this association can be confirmed it is the first known case of disease caused by a virus previously considered pathogenic only to plants. Diagnosis and treatment [ edit ] Viral disease is usually detected by clinical presentation, for instance, severe muscle and joint pains preceding fever, or skin rash and swollen lymph glands.
5 days ago · Virus classification is the process of naming viruses and placing them into a taxonomic system similar to the classification systems used for cellular organisms. Viruses are mainly classified by phenotypic characteristics, such as morphology , nucleic acid type, mode of replication, host organisms , and the type of disease they cause.
4 days ago · Notable members include West Nile virus, Dengue virus, Chikungunya, Severe acute respiratory syndrome (SARS) Coronavirus and enteroviruses of the Picornaviridae family.Unfortunately, prophylactic ...