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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
- Figure - PMC - National Center for Biotechnology Information
The pathogenesis of dengue virus infection is attributed to...
- Molecular characteristics and replication mechanism of dengue ...
As a consequence about the previously reviewed information,...
- Figure - PMC - National Center for Biotechnology Information
Dengue virus is a relatively simple positive-sense single-stranded RNA virus that is 50 nm in diameter and has three structural proteins — capsid (C) protein, precursor membrane (prM) protein...
- Gavin Screaton, Juthathip Mongkolsapaya, Juthathip Mongkolsapaya, Sophie Yacoub, Sophie Yacoub, Cath...
- 2015
Nov 19, 2023 · The Life Cycle of Dengue Virus. (Dengue virus enters the host by receptor-mediated endocytosis, which subsequently results in the fusion of vesicular and viral membranes. This fusion allows the secretion of genomic RNA into the cytoplasm, which plays a role as mRNA for replication and translation.
Mar 18, 2022 · Abstract. Knowledge of contemporary genetic composition of dengue virus (DENV) in Africa is lacking. By using next-generation sequencing of samples from the 2017 DENV outbreak in Burkina Faso, we isolated 29 DENV genomes (5 serotype 1, 16 serotype 2 [DENV-2], and 8 serotype 3).
Apr 1, 2022 · During the past three decades, different pathways of innate immunity have been identified in Aedes spp. Recognition of viral molecular patterns, including viral RNA, and vector attempts to resist DENV infection are the most important defense mechanisms.
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Aug 18, 2016 · 89 Altmetric. Metrics. Abstract. Dengue is widespread throughout the tropics and local spatial variation in dengue virus transmission is strongly influenced by rainfall, temperature,...
